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Literature DB >> 27686015

Toward an Effective Ebola Virus Vaccine.

Rohan Keshwara¹, Reed F Johnson², Matthias J Schnell¹.

Abstract

Long-term control of viral outbreaks requires the use of vaccines to impart acquired resistance and ensuing protection. In the wake of an epidemic, established immunity against a particular disease can limit spread and significantly decrease mortality. Creation of a safe and efficacious vaccine against Ebola virus (EBOV) has proven elusive so far, but various inventive strategies are now being employed to counteract the threat of outbreaks caused by EBOV and related filoviruses. Here, we present a current overview of progress in the field of Ebola virus vaccine development.

Entities: Species

Keywords: EBOV vaccine; immunization; vector

Mesh：

Substances：

Year: 2016 PMID： 27686015 DOI： 10.1146/annurev-med-051215-030919

Source DB: PubMed Journal: Annu Rev Med ISSN： 0066-4219 Impact factor: 13.739

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Cited

11 in total

1. A Recombinant Rabies Virus Expressing the Marburg Virus Glycoprotein Is Dependent upon Antibody-Mediated Cellular Cytotoxicity for Protection against Marburg Virus Disease in a Murine Model.

Authors: Rohan Keshwara; Katie R Hagen; Tiago Abreu-Mota; Amy B Papaneri; David Liu; Christoph Wirblich; Reed F Johnson; Matthias J Schnell
Journal: J Virol Date: 2019-03-05 Impact factor: 5.103

2. Intradermal Vaccination With Adjuvanted Ebola Virus Soluble Glycoprotein Subunit Vaccine by Microneedle Patches Protects Mice Against Lethal Ebola Virus Challenge.

Authors: Ying Liu; Ling Ye; Fang Lin; Yasmine Gomaa; David Flyer; Ricardo Carrion; Jean L Patterson; Mark R Prausnitz; Gale Smith; Gregory Glenn; Hua Wu; Richard W Compans; Chinglai Yang
Journal: J Infect Dis Date: 2018-11-22 Impact factor: 5.226

Review 3. Fighting Ebola: A Window for Vaccine Re-evaluation?

Authors: Keith J Chappell; Daniel Watterson
Journal: PLoS Pathog Date: 2017-01-12 Impact factor: 6.823

4. An adenovirus serotype 2-vectored ebolavirus vaccine generates robust antibody and cell-mediated immune responses in mice and rhesus macaques.

Authors: Yupeng Feng; Chufang Li; Peiyu Hu; Qian Wang; Xuehua Zheng; Yongkun Zhao; Yi Shi; Songtao Yang; Changhua Yi; Ying Feng; Chunxiu Wu; Linbing Qu; Wei Xu; Yao Li; Caijun Sun; Fu Geroge Gao; Xianzhu Xia; Liqiang Feng; Ling Chen
Journal: Emerg Microbes Infect Date: 2018-06-06 Impact factor: 7.163

Review 5. Assessing the Importance of Domestic Vaccine Manufacturing Centers: An Overview of Immunization Programs, Vaccine Manufacture, and Distribution.

Authors: Emma Rey-Jurado; Felipe Tapia; Natalia Muñoz-Durango; Margarita K Lay; Leandro J Carreño; Claudia A Riedel; Susan M Bueno; Yvonne Genzel; Alexis M Kalergis
Journal: Front Immunol Date: 2018-01-18 Impact factor: 7.561

6. Development, qualification, and validation of the Filovirus Animal Nonclinical Group anti-Ebola virus glycoprotein immunoglobulin G enzyme-linked immunosorbent assay for human serum samples.

Authors: Thomas L Rudge; Karen A Sankovich; Nancy A Niemuth; Michael S Anderson; Christopher S Badorrek; Nick D Skomrock; Chris M Cirimotich; Carol L Sabourin
Journal: PLoS One Date: 2019-04-18 Impact factor: 3.240

Review 7. Research Advances on the Interactions between Rabies Virus Structural Proteins and Host Target Cells: Accrued Knowledge from the Application of Reverse Genetics Systems.

Authors: Juanbin Yin; Xiangwei Wang; Ruoqing Mao; Zhixiong Zhang; Xin Gao; Yingying Luo; Yuefeng Sun; Xiangping Yin
Journal: Viruses Date: 2021-11-16 Impact factor: 5.048