| Literature DB >> 27685633 |
Zuozhang Yang1, Xiaojuan Li1, Yihao Yang1, Zewei He1, Xin Qu1, Ya Zhang1.
Abstract
Long noncoding RNAs (lncRNAs) are a class of non-protein-coding molecules longer than 200 nucleotides that are involved in the development and progression of many types of tumors. Numerous lncRNAs regulate cell proliferation, metastasis, and chemotherapeutic drug resistance. Osteosarcoma is one of the main bone tumor subtypes that poses a serious threat to adolescent health. We summarized how lncRNAs regulate osteosarcoma progression, invasion, and drug resistance, as well as how lncRNAs can function as biomarkers or independent prognostic indicators with respect to osteosarcoma therapy.Entities:
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Year: 2016 PMID： 27685633 PMCID： PMC5059871 DOI： 10.1038/cddis.2016.272
Source DB: PubMed Journal: Cell Death Dis Impact factor: 8.469