Literature DB >> 27682064

Home Environment as a Source of Life-Threatening Azole-Resistant Aspergillus fumigatus in Immunocompromised Patients.

Rose-Anne Lavergne1,2, Taieb Chouaki3,4, Ferry Hagen5, Bénédicte Toublanc6, Hervé Dupont7,8, Vincent Jounieaux6, Jacques F Meis5,9, Florent Morio1,2, Patrice Le Pape1,2.   

Abstract

A case of fatal aspergillosis due to a TR46/Y121F/T289A azole-resistant Aspergillus fumigatus is reported. Environmental investigations at the patient's residence led to the recovery of TR46/Y121F/T289A isolates, genotypically indistinguishable from the clinical isolate, supporting for the first time the direct role of household as potential source of azole-resistant invasive aspergillosis.
© The Author 2016. Published by Oxford University Press for the Infectious Diseases Society of America. All rights reserved. For permissions, e-mail journals.permissions@oup.com.

Entities:  

Keywords:  Aspergillus fumigatus; TR46/Y121F/T289A; azole resistance; environment; invasive aspergillosis

Mesh：

Substances：

Year:  2016        PMID： 27682064     DOI： 10.1093/cid/ciw664

Source DB:  PubMed          Journal:  Clin Infect Dis        ISSN： 1058-4838            Impact factor:   9.079


  13 in total

Review 1.  Clinical implications of globally emerging azole resistance in Aspergillus fumigatus.

Authors:  Jacques F Meis; Anuradha Chowdhary; Johanna L Rhodes; Matthew C Fisher; Paul E Verweij
Journal:  Philos Trans R Soc Lond B Biol Sci       Date:  2016-12-05       Impact factor: 6.237

Review 2.  Emerging threat of triazole-resistant Aspergillus fumigatus.

Authors:  Jeffrey M Rybak; Jarrod R Fortwendel; P David Rogers
Journal:  J Antimicrob Chemother       Date:  2019-04-01       Impact factor: 5.790

Review 3.  Investigating Clinical Issues by Genotyping of Medically Important Fungi: Why and How?

Authors:  Alexandre Alanio; Marie Desnos-Ollivier; Dea Garcia-Hermoso; Stéphane Bretagne
Journal:  Clin Microbiol Rev       Date:  2017-07       Impact factor: 26.132

Review 4.  Aspergillus fumigatus and aspergillosis: From basics to clinics.

Authors:  A Arastehfar; A Carvalho; J Houbraken; L Lombardi; R Garcia-Rubio; J D Jenks; O Rivero-Menendez; R Aljohani; I D Jacobsen; J Berman; N Osherov; M T Hedayati; M Ilkit; D James-Armstrong; T Gabaldón; J Meletiadis; M Kostrzewa; W Pan; C Lass-Flörl; D S Perlin; M Hoenigl
Journal:  Stud Mycol       Date:  2021-05-10       Impact factor: 16.097

Review 5.  Azole Resistance in Aspergillus fumigatus in Patients with Cystic Fibrosis: A Matter of Concern?

Authors:  A Hamprecht; F Morio; O Bader; P Le Pape; J Steinmann; E Dannaoui
Journal:  Mycopathologia       Date:  2017-06-26       Impact factor: 2.574

6.  New Antifungal Susceptibility Test Based on Chitin Detection by Image Cytometry.

Authors:  Yan Wang; Arisandy N Andriampamonjy; Sebastien Bailly; Cécile Garnaud; Danièle Maubon; Muriel Cornet; Delphine Aldebert
Journal:  Antimicrob Agents Chemother       Date:  2019-12-20       Impact factor: 5.191

Review 7.  Challenges in microbiological diagnosis of invasive Aspergillus infections.

Authors:  Alexandre Alanio; Stéphane Bretagne
Journal:  F1000Res       Date:  2017-02-17

8.  Strengthening the One Health Agenda: The Role of Molecular Epidemiology in Aspergillus Threat Management.

Authors:  Eta E Ashu; Jianping Xu
Journal:  Genes (Basel)       Date:  2018-07-19       Impact factor: 4.096

9.  Nonrandom Distribution of Azole Resistance across the Global Population of Aspergillus fumigatus.

Authors:  Thomas R Sewell; Jianing Zhu; Johanna Rhodes; Ferry Hagen; Jacques F Meis; Matthew C Fisher; Thibaut Jombart
Journal:  mBio       Date:  2019-05-21       Impact factor: 7.867

Review 10.  Invasive Fungal Infections in Patients with Hematological Malignancies: Emergence of Resistant Pathogens and New Antifungal Therapies.

Authors:  Maria N Gamaletsou; Thomas J Walsh; Nikolaos V Sipsas
Journal:  Turk J Haematol       Date:  2018-02-02       Impact factor: 1.831
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