Literature DB >> 27681784

Merck &Co. drops osteoporosis drug odanacatib.

Asher Mullard.   

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Year:  2016        PMID： 27681784     DOI： 10.1038/nrd.2016.207

Source DB:  PubMed          Journal:  Nat Rev Drug Discov        ISSN： 1474-1776            Impact factor:   84.694


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  35 in total

Review 1.  Coupling factors involved in preserving bone balance.

Authors:  Beom-Jun Kim; Jung-Min Koh
Journal:  Cell Mol Life Sci       Date:  2018-12-04       Impact factor: 9.261

Review 2.  Osteoporosis treatment: recent developments and ongoing challenges.

Authors:  Sundeep Khosla; Lorenz C Hofbauer
Journal:  Lancet Diabetes Endocrinol       Date:  2017-07-07       Impact factor: 32.069

Review 3.  Inhibiting Cellular Senescence: A New Therapeutic Paradigm for Age-Related Osteoporosis.

Authors:  Sundeep Khosla; Joshua N Farr; James L Kirkland
Journal:  J Clin Endocrinol Metab       Date:  2018-04-01       Impact factor: 5.958

4.  Tanshinones that selectively block the collagenase activity of cathepsin K provide a novel class of ectosteric antiresorptive agents for bone.

Authors:  Preety Panwar; Simon Law; Andrew Jamroz; Pouya Azizi; Dongwei Zhang; Marco Ciufolini; Dieter Brömme
Journal:  Br J Pharmacol       Date:  2018-02-09       Impact factor: 8.739

5.  Role of osteoclasts in oral homeostasis and jawbone diseases.

Authors:  Maiko Omi; Yuji Mishina
Journal:  Oral Sci Int       Date:  2020-07-21

6.  Reassessing enzyme kinetics: Considering protease-as-substrate interactions in proteolytic networks.

Authors:  Meghan C Ferrall-Fairbanks; Chris A Kieslich; Manu O Platt
Journal:  Proc Natl Acad Sci U S A       Date:  2020-01-24       Impact factor: 11.205

7.  Discovery of a Small Molecule Promoting Mouse and Human Osteoblast Differentiation via Activation of p38 MAPK-β.

Authors:  Brandoch Cook; Ruhina Rafiq; Heejin Lee; Kelly M Banks; Mohammed El-Debs; Jeanne Chiaravalli; J Fraser Glickman; Bhaskar C Das; Shuibing Chen; Todd Evans
Journal:  Cell Chem Biol       Date:  2019-04-25       Impact factor: 8.116

Review 8.  Amide Bond Bioisosteres: Strategies, Synthesis, and Successes.

Authors:  Shikha Kumari; Angelica V Carmona; Amit K Tiwari; Paul C Trippier
Journal:  J Med Chem       Date:  2020-08-04       Impact factor: 7.446

9.  Cellular senescence in bone.

Authors:  Joshua N Farr; Sundeep Khosla
Journal:  Bone       Date:  2019-01-16       Impact factor: 4.398

Review 10.  Osteogenesis imperfecta and therapeutics.

Authors:  Roy Morello
Journal:  Matrix Biol       Date:  2018-03-11       Impact factor: 11.583
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