Literature DB >> 27681445

MPD3: a useful medicinal plants database for drug designing.

Arooj Mumtaz1,2, Usman Ali Ashfaq1, Muhammad Tahir Ul Qamar1,3, Farooq Anwar4,5, Faisal Gulzar6, Muhammad Amjad Ali3,7, Nazamid Saari8, Muhammad Tariq Pervez2.   

Abstract

Medicinal plants are the main natural pools for the discovery and development of new drugs. In the modern era of computer-aided drug designing (CADD), there is need of prompt efforts to design and construct useful database management system that allows proper data storage, retrieval and management with user-friendly interface. An inclusive database having information about classification, activity and ready-to-dock library of medicinal plant's phytochemicals is therefore required to assist the researchers in the field of CADD. The present work was designed to merge activities of phytochemicals from medicinal plants, their targets and literature references into a single comprehensive database named as Medicinal Plants Database for Drug Designing (MPD3). The newly designed online and downloadable MPD3 contains information about more than 5000 phytochemicals from around 1000 medicinal plants with 80 different activities, more than 900 literature references and 200 plus targets. The designed database is deemed to be very useful for the researchers who are engaged in medicinal plants research, CADD and drug discovery/development with ease of operation and increased efficiency. The designed MPD3 is a comprehensive database which provides most of the information related to the medicinal plants at a single platform. MPD3 is freely available at: http://bioinform.info .

Entities:  

Keywords:  Medicinal plants; database management system; drug designing; phytochemicals; ready to dock phytochemical library

Mesh:

Substances:

Year:  2016        PMID: 27681445     DOI: 10.1080/14786419.2016.1233409

Source DB:  PubMed          Journal:  Nat Prod Res        ISSN: 1478-6419            Impact factor:   2.861


  19 in total

1.  Computational screening of medicinal plant phytochemicals to discover potent pan-serotype inhibitors against dengue virus.

Authors:  Muhammad Tahir Ul Qamar; Arooma Maryam; Iqra Muneer; Feng Xing; Usman Ali Ashfaq; Faheem Ahmed Khan; Farooq Anwar; Mohammed H Geesi; Rana Rehan Khalid; Sadaf Abdul Rauf; Abdul Rauf Siddiqi
Journal:  Sci Rep       Date:  2019-02-05       Impact factor: 4.379

Review 2.  Nanoscale Technologies in the Fight against COVID-19: From Innovative Nanomaterials to Computer-Aided Discovery of Potential Antiviral Plant-Derived Drugs.

Authors:  Nunzio Iraci; Carmelo Corsaro; Salvatore V Giofrè; Giulia Neri; Angela Maria Mezzasalma; Martina Vacalebre; Antonio Speciale; Antonina Saija; Francesco Cimino; Enza Fazio
Journal:  Biomolecules       Date:  2022-07-30

3.  Discovery of Rift Valley fever virus natural pan-inhibitors by targeting its multiple key proteins through computational approaches.

Authors:  Israr Fatima; Sajjad Ahmad; Mubarak A Alamri; Muhammad Usman Mirza; Muhammad Tahir Ul Qamar; Abdur Rehman; Farah Shahid; Eid A Alatawi; Faris F Aba Alkhayl; Wafa Abdullah Al-Megrin; Ahmad Almatroudi
Journal:  Sci Rep       Date:  2022-06-03       Impact factor: 4.996

4.  Promising terpenes as SARS-CoV-2 spike receptor-binding domain (RBD) attachment inhibitors to the human ACE2 receptor: Integrated computational approach.

Authors:  Ziyad Tariq Muhseen; Alaa R Hameed; Halah M H Al-Hasani; Muhammad Tahir Ul Qamar; Guanglin Li
Journal:  J Mol Liq       Date:  2020-10-07       Impact factor: 6.165

5.  The effects of genotypes and media composition on callogenesis, regeneration and cell suspension culture of chamomile (Matricaria chamomilla L.).

Authors:  Aqeel Ahmad; Muhammad Tahir Ul Qamar; Almeera Shoukat; Mehtab Muhammad Aslam; Mohsin Tariq; Mansor Hakiman; Faiz Ahmad Joyia
Journal:  PeerJ       Date:  2021-05-24       Impact factor: 2.984

6.  Analysis of Bos taurus and Sus scrofa X and Y chromosome transcriptome highlights reproductive driver genes.

Authors:  Faheem Ahmed Khan; Hui Liu; Hao Zhou; Kai Wang; Muhammad Tahir Ul Qamar; Nuruliarizki Shinta Pandupuspitasari; Zhang Shujun
Journal:  Oncotarget       Date:  2017-04-13

7.  Structural basis of SARS-CoV-2 3CLpro and anti-COVID-19 drug discovery from medicinal plants.

Authors:  Muhammad Tahir Ul Qamar; Safar M Alqahtani; Mubarak A Alamri; Ling-Ling Chen
Journal:  J Pharm Anal       Date:  2020-03-26

8.  Ethnobotanical study and phytochemical profiling of Heptapleurum hypoleucum leaf extract and evaluation of its antimicrobial activities against diarrhea-causing bacteria.

Authors:  S M Rakib-Uz-Zaman; Asif Iqbal; Sadrina Afrin Mowna; Mst Gitika Khanom; Mohammad Mastak Al Amin; Kashmery Khan
Journal:  J Genet Eng Biotechnol       Date:  2020-06-15

9.  Promising Terpenes as Natural Antagonists of Cancer: An In-Silico Approach.

Authors:  Ziyad Tariq Muhseen; Guanglin Li
Journal:  Molecules       Date:  2019-12-30       Impact factor: 4.411

10.  Phytochemicals from Selective Plants Have Promising Potential against SARS-CoV-2: Investigation and Corroboration through Molecular Docking, MD Simulations, and Quantum Computations.

Authors:  Kafila Kousar; Arshia Majeed; Farkhanda Yasmin; Waqar Hussain; Nouman Rasool
Journal:  Biomed Res Int       Date:  2020-10-13       Impact factor: 3.411

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