Literature DB >> 27679745

Documentation of various approaches and outcomes in patients on warfarin undergoing dental procedures: a review article.

Fayez El Shaer1, Ismael Raslan1, Nora Al Osaimi1, Ghada Bawazeer1, Fhakr Alayobi1, Tarek Alhogbani1, Suliman Kharabsheh1, Walid Al Habeeb1.   

Abstract

Appropriate management of patients with mechanical prosthetic valves on warfarin during dental procedures is crucial. If the patients continue warfarin, they might develop bleeding, while interruption of therapy can cause thromboembolic events. Bridging therapy (mostly heparin) is used in some patients, while others stop medications. There is no unifying protocol. Information on management of patients on warfarin undergoing dental procedures in Saudi Arabia is lacking. Therefore, the current study aimed to provide more insight into various approaches utilized by clinicians to deal with such patients at a large teaching hospital in Riyadh, and to evaluate the frequency and severity of bleeding and thromboembolic complications during different types of dental procedures in this population. This was a cohort study. Patient records were used to collect data on peri-procedural management of patients on warfarin, continuation or interruption of warfarin therapy, as well as bleeding and thromboembolic complications. Fifty medical records were reviewed from March to October 2012. Regarding management, 10% had no proper documentation, 74% underwent bridging therapy, 12% discontinued warfarin therapy, and 4% continued warfarin. Of the patients, 31% had minor bleeding (15% in patients on bridging therapy and 16% in patients continuing warfarin). Thromboembolic complications were documented in 4%, (2% in those on bridging therapy and 2% in those discontinuing warfarin). Patients on bridging therapy (heparin) were admitted to the hospital for a mean of five days, and none of the other patients were admitted. Adopting the protocol to continue warfarin caused bleeding tendency that was controlled with the usual measures, with more cost effectiveness, and no thromboembolic risks.

Entities:  

Keywords:  Dental procedures; bridging therapy; complications; heparin; warfarin

Year:  2016        PMID: 27679745      PMCID: PMC5030390     

Source DB:  PubMed          Journal:  Am J Cardiovasc Dis        ISSN: 2160-200X


  46 in total

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Journal:  Mayo Clin Proc       Date:  2003-11       Impact factor: 7.616

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Authors:  Marieke Torn; Frits R Rosendaal
Journal:  Br J Haematol       Date:  2003-11       Impact factor: 6.998

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Authors:  Justin K Nelms; Anna I Wooten; Frederick Heckler
Journal:  Ann Plast Surg       Date:  2009-03       Impact factor: 1.539

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