Literature DB >> 27678496

Inadvertent spinal injection of ondansetron.

May-Han Loh1, Lyn Li Lean2, Bryan Su Wei Ng1, Will Ne-Hooi Loh1.   

Abstract

Cesarean sections under spinal anesthesia are now a daily occurrence in most tertiary hospitals. We report the first published case of inadvertent spinal injection of ondansetron without any neurological sequelae in a patient undergoing elective Cesarean section under spinal anesthesia. She did not experience any permanent neurological sequelae, and also did not exhibit any central neuraxial opioid side effects-nausea, vomiting or pruritus. Vigilance is essential to reduce the risk of wrong route delivery of drugs, especially when presented in very similar-looking 2 mL ampules as in our institution.

Entities:  

Keywords:  Anesthesia; Injection; Intrathecal; Ondansetron hydrochloride; Spinal

Mesh:

Substances:

Year:  2016        PMID: 27678496     DOI: 10.1007/s00540-016-2254-6

Source DB:  PubMed          Journal:  J Anesth        ISSN: 0913-8668            Impact factor:   2.078


  14 in total

1.  Inadvertent epidural injection of ondansetron.

Authors:  Jeffrey J Huang
Journal:  J Clin Anesth       Date:  2006-05       Impact factor: 9.452

2.  Accidental intrathecal injection of aminophylline in spinal anesthesia.

Authors:  Muhammad Ajmal
Journal:  Anesthesiology       Date:  2011-04       Impact factor: 7.892

3.  What epidural opioid results in the best analgesia outcomes and fewest side effects after surgery?: a meta-analysis of randomized controlled trials.

Authors:  Nayer Youssef; David Orlov; Tristan Alie; Matthew Chong; Ji Cheng; Lehana Thabane; James Paul
Journal:  Anesth Analg       Date:  2014-10       Impact factor: 5.108

4.  Accidental intrathecal injection of bupivacaine and dextran.

Authors:  P J Evans; J W Lloyd; G J Wood
Journal:  Anaesthesia       Date:  1981-07       Impact factor: 6.955

5.  Behavioural testing and histological assessments of rabbit spinal cord following intrathecal administration of ondansetron.

Authors:  Hector J Lacassie; John R Schultz; Thomas J Cummings; Richard Morris; Scott L Trasti; James D Reynolds
Journal:  Clin Exp Pharmacol Physiol       Date:  2006-09       Impact factor: 2.557

6.  Lack of analgesic efficacy of spinal ondansetron on thermal and mechanical hypersensitivity following spinal nerve ligation in the rat.

Authors:  Christopher M Peters; Ken-ichiro Hayashida; Eric E Ewan; Kunie Nakajima; Hideaki Obata; Qinghao Xu; Tony L Yaksh; James C Eisenach
Journal:  Brain Res       Date:  2010-07-15       Impact factor: 3.252

Review 7.  Severe adhesive arachnoiditis resulting in progressive paraplegia following obstetric spinal anaesthesia: a case report and review.

Authors:  T Killeen; A Kamat; D Walsh; A Parker; A Aliashkevich
Journal:  Anaesthesia       Date:  2012-10-12       Impact factor: 6.955

Review 8.  Serotonin receptor antagonists for the prevention and treatment of pruritus, nausea, and vomiting in women undergoing cesarean delivery with intrathecal morphine: a systematic review and meta-analysis.

Authors:  Ronald B George; Terrence K Allen; Ashraf S Habib
Journal:  Anesth Analg       Date:  2009-07       Impact factor: 5.108

Review 9.  Effect of prophylactic 5-HT3 receptor antagonists on pruritus induced by neuraxial opioids: a quantitative systematic review.

Authors:  M-P Bonnet; E Marret; J Josserand; F J Mercier
Journal:  Br J Anaesth       Date:  2008-07-07       Impact factor: 9.166

Review 10.  Ondansetron clinical pharmacokinetics.

Authors:  F Roila; A Del Favero
Journal:  Clin Pharmacokinet       Date:  1995-08       Impact factor: 6.447

View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.