| Literature DB >> 27677365 |
M Mazidi1,2, A Heidari-Bakavoli3, S S Khayyatzadeh4, M R Azarpazhooh4, M Nematy4, M Safarian4, H Esmaeili5, S M R Parizadeh4, M Ghayour-Mobarhan4, A P Kengne6, G A Ferns7.
Abstract
The objective of this study was to investigate whether serum high-sensitivity C-reactive protein (hs-CRP) concentration varies with dietary fatty acid intake in Iranian adults free of any history of cardiovascular disease (CVD). This cross-sectional study involved 8105 adults (3142 men) aged 35-65 years. Dietary intake was assessed using 24-h dietary recalls. The relationship between anthropometric, cardiometabolic risk factors and dietary data and serum hs-CRP was assessed using SPSS software. Median crude dietary saturated fat decreased across hs-CRP quarters (P =0.009 for linear trend), whereas energy-adjusted total fat (P =0.017), trans-fat (P =0.016), monounsaturated fatty acids (P =0.030) and cholesterol (P =0.005) monotonically increased, with some evidence of statistical interactions by gender. In conclusion, serum hs-CRP concentrations were associated with some components of dietary fatty acid intake in our population of individuals without CVD, suggesting that dietary fat intake could be associated with subclinical inflammation.Entities:
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Year: 2016 PMID： 27677365 DOI： 10.1038/ejcn.2016.92
Source DB: PubMed Journal: Eur J Clin Nutr ISSN： 0954-3007 Impact factor: 4.016