Nicole Berger1, Sibylle Dubach Schwizer2, Zsuzsanna Varga3, Christoph Rageth4, Thomas Frauenfelder5, Andreas Boss6. 1. Institute of Diagnostic and Interventional Radiology, University Hospital Zurich, Raemistrasse 100, 8091 Zurich, Switzerland; Breast Center Zurich, Seefeldstrasse 214, 8008 Zurich, Switzerland. Electronic address: nicole.berger@usz.ch. 2. Breast Center Zurich, Seefeldstrasse 214, 8008 Zurich, Switzerland. Electronic address: s.dubach@brustzentrum.ch. 3. Institute of Surgical Pathology, University Hospital Zurich, Raemistrasse 100, 8091 Zurich, Switzerland. Electronic address: zsuzsanna.varga@usz.ch. 4. Breast Center Zurich, Seefeldstrasse 214, 8008 Zurich, Switzerland. Electronic address: c.rageth@brust-zentrum.ch. 5. Institute of Diagnostic and Interventional Radiology, University Hospital Zurich, Raemistrasse 100, 8091 Zurich, Switzerland. Electronic address: thomas.frauenfelder@usz.ch. 6. Institute of Diagnostic and Interventional Radiology, University Hospital Zurich, Raemistrasse 100, 8091 Zurich, Switzerland. Electronic address: andreas.boss@usz.ch.
Abstract
OBJECTIVES: The objective was to determine if digital tomosynthesis of the breast (DBT) assesses the extension of ductal carcinoma in situ (DCIS) with higher precision than mammography (MG). MATERIAL AND METHODS: The local ethics committee approved this retrospective study including 26 patients with DCIS, which were rated by three radiologists. Statistics were performed using intraclass correlation (ICC) for interreader agreement and the Pearson correlation for correlation of MG and DBT. Standard of reference was the histologic extension. RESULTS: The ICC was excellent. Correlation between MG and histology was 0.879 (P<.01) and for DBT and histology was 0.914 (P<.01). CONCLUSION: DBT provides a slightly better estimation of the size of a DCIS than MG.
OBJECTIVES: The objective was to determine if digital tomosynthesis of the breast (DBT) assesses the extension of ductal carcinoma in situ (DCIS) with higher precision than mammography (MG). MATERIAL AND METHODS: The local ethics committee approved this retrospective study including 26 patients with DCIS, which were rated by three radiologists. Statistics were performed using intraclass correlation (ICC) for interreader agreement and the Pearson correlation for correlation of MG and DBT. Standard of reference was the histologic extension. RESULTS: The ICC was excellent. Correlation between MG and histology was 0.879 (P<.01) and for DBT and histology was 0.914 (P<.01). CONCLUSION: DBT provides a slightly better estimation of the size of a DCIS than MG.