Literature DB >> 27673409

MicroRNA and Long Non-Coding RNA in Ovarian Carcinoma: Translational Insights and Potential Clinical Applications.

Yu Ma1, Yan Lu2, Bingjian Lu3.   

Abstract

Reliable biomarkers for the detection of early ovarian carcinoma are currently unavailable. MicroRNA and long non-coding RNA may be important in cancer initiation and progression by regulating gene expression through post-transcriptional mechanisms. MicroRNAs, such as miR-26a and miR-132, have been investigated as novel biomarkers for diagnosis, prognosis, monitoring of therapeutic response, and therapeutic targets in ovarian carcinomas. Some long non-coding RNAs, such as H19 and UCA1, may be involved in the pathogenesis of ovarian carcinomas. MicroRNA and long non-coding RNA have potential clinical utility in the diagnosis of ovarian cancer and predicting prognosis, metastasis, recurrence, and response to therapy.

Entities:  

Keywords:  Ovarian carcinoma; biomarkers; long non-coding RNA; microRNA

Mesh：

Substances：

Year:  2016        PMID： 27673409     DOI： 10.1080/07357907.2016.1227446

Source DB:  PubMed          Journal:  Cancer Invest        ISSN： 0735-7907            Impact factor:   2.176


  6 in total

1.  GAS5 functions as a ceRNA to regulate hZIP1 expression by sponging miR-223 in clear cell renal cell carcinoma.

Authors:  Xiao Dong; Chuize Kong; Xiankui Liu; Jianbin Bi; Zhenhua Li; Zeliang Li; Yuyan Zhu; Zhe Zhang
Journal:  Am J Cancer Res       Date:  2018-08-01       Impact factor: 6.166

2.  Microarray analysis reveals differentially expressed lncRNAs in benign epithelial ovarian cysts and normal ovaries.

Authors:  Xiaoguang Liu; Chencheng Dai; Genmei Jia; Sujuan Xu; Ziyi Fu; Juan Xu; Qing Li; Hongjie Ruan; Pengfei Xu
Journal:  Oncol Rep       Date:  2017-06-22       Impact factor: 3.906

3.  The long non-coding RNA AK023948 enhances tumor progression in hepatocellular carcinoma.

Authors:  Bailiang Ye; Bingren Hu; Zhihai Zheng; Ru Zheng; Yixiong Shi
Journal:  Exp Ther Med       Date:  2017-08-24       Impact factor: 2.447

4.  LncRNA PVT1 promotes ovarian cancer progression by silencing miR-214.

Authors:  Ying Chen; Hui Du; Lewen Bao; Wenxin Liu
Journal:  Cancer Biol Med       Date:  2018-08       Impact factor: 4.248

5.  Long non-coding RNA PCAT6 targets miR-204 to modulate the chemoresistance of colorectal cancer cells to 5-fluorouracil-based treatment through HMGA2 signaling.

Authors:  Haijun Wu; Qiongyan Zou; Hong He; Yu Liang; Mingjun Lei; Qin Zhou; Dan Fan; Liangfang Shen
Journal:  Cancer Med       Date:  2019-04-01       Impact factor: 4.452

6.  Long Non-Coding RNA MAGI2-AS3 is a New Player with a Tumor Suppressive Role in High Grade Serous Ovarian Carcinoma.

Authors:  Priyanka Gokulnath; Tiziana de Cristofaro; Ichcha Manipur; Tina Di Palma; Amata Amy Soriano; Mario Rosario Guarracino; Mariastella Zannini
Journal:  Cancers (Basel)       Date:  2019-12-12       Impact factor: 6.639
  6 in total

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