Literature DB >> 27671007

Up-date on the NeoVitaA Trial: Obstacles, challenges, perspectives, and local experiences.

Sascha Meyer1, Ludwig Gortner2.   

Abstract

The aim of the NeoVitaA Trial is to assess the role of postnatal additional high-dose oral vitamin A supplementation for 28 days in reducing Bronchopulmonary dysplasia (BPD) or death in extremely low birth weight (ELBW) infants at 36 weeks postmenstrual age (PMA). All infants (both intervention and control group) will be provided with basic vitamin A (1000 IU/kg/day) in addition to trial intervention.In this short communication, we will give an up-date on obstacles, challenges as well as perspectives and potential solutions when putting into place a multicenter, double-blind, randomized trial in this cohort of extremely susceptible infants.

Entities:  

Keywords:  Bronchopulmonary dysplasia; Extremely low birth weight infants; Vitamin A

Mesh:

Substances:

Year:  2016        PMID: 27671007     DOI: 10.1007/s10354-016-0500-z

Source DB:  PubMed          Journal:  Wien Med Wochenschr        ISSN: 0043-5341


  20 in total

1.  Policy statement--postnatal corticosteroids to prevent or treat bronchopulmonary dysplasia.

Authors:  Kristi L Watterberg
Journal:  Pediatrics       Date:  2010-09-06       Impact factor: 7.124

2.  Rates of bronchopulmonary dysplasia in very preterm neonates in Europe: results from the MOSAIC cohort.

Authors:  Ludwig Gortner; Björn Misselwitz; David Milligan; Jennifer Zeitlin; Louis Kollée; Klaus Boerch; Rocco Agostino; Patrick Van Reempts; Jean-Louis Chabernaud; Gérard Bréart; Emile Papiernik; Pierre-Henri Jarreau; Manuel Carrapato; Janusz Gadzinowski; Elizabeth Draper
Journal:  Neonatology       Date:  2010-08-23       Impact factor: 4.035

3.  Trends in severe bronchopulmonary dysplasia rates between 1994 and 2002.

Authors:  Vincent C Smith; John A F Zupancic; Marie C McCormick; Lisa A Croen; John Greene; Gabriel J Escobar; Douglas K Richardson
Journal:  J Pediatr       Date:  2005-04       Impact factor: 4.406

Review 4.  Function of vitamin A in vertebrate embryonic development.

Authors:  M H Zile
Journal:  J Nutr       Date:  2001-03       Impact factor: 4.798

5.  Effects of early inhaled nitric oxide therapy and vitamin A supplementation on the risk for bronchopulmonary dysplasia in premature newborns with respiratory failure.

Authors:  Monika M Gadhia; Gary R Cutter; Steven H Abman; John P Kinsella
Journal:  J Pediatr       Date:  2013-12-31       Impact factor: 4.406

Review 6.  Vitamin A supplementation to prevent mortality and short- and long-term morbidity in very low birthweight infants.

Authors:  Brian A Darlow; P J Graham
Journal:  Cochrane Database Syst Rev       Date:  2011-10-05

7.  Understanding variation in vitamin A supplementation among NICUs.

Authors:  Heather C Kaplan; Meredith E Tabangin; Diana McClendon; Jareen Meinzen-Derr; Peter A Margolis; Edward F Donovan
Journal:  Pediatrics       Date:  2010-07-05       Impact factor: 7.124

8.  Vitamin A supplementation for extremely-low-birth-weight infants. National Institute of Child Health and Human Development Neonatal Research Network.

Authors:  J E Tyson; L L Wright; W Oh; K A Kennedy; L Mele; R A Ehrenkranz; B J Stoll; J A Lemons; D K Stevenson; C R Bauer; S B Korones; A A Fanaroff
Journal:  N Engl J Med       Date:  1999-06-24       Impact factor: 91.245

Review 9.  Management of infants with bronchopulmonary dysplasia in Germany.

Authors:  Wolfgang Thomas; Christian P Speer
Journal:  Early Hum Dev       Date:  2005-01-18       Impact factor: 2.079

10.  Retinoic acid differentially regulates expression of surfactant-associated proteins in human fetal lung.

Authors:  M D Metzler; J M Snyder
Journal:  Endocrinology       Date:  1993-11       Impact factor: 4.736

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  7 in total

1.  Intramuscular Followed by Oral Vitamin A Supplementation in Neonates with Birth Weight from 750 to 1250 g: A Randomized Controlled Trial.

Authors:  S Giridhar; Jogender Kumar; Savita Verma Attri; Sourabh Dutta; Praveen Kumar
Journal:  Indian J Clin Biochem       Date:  2019-01-03

Review 2.  Bronchopulmonary Dysplasia: Chronic Lung Disease of Infancy and Long-Term Pulmonary Outcomes.

Authors:  Lauren M Davidson; Sara K Berkelhamer
Journal:  J Clin Med       Date:  2017-01-06       Impact factor: 4.241

3.  Vitamin A to prevent bronchopulmonary dysplasia in extremely low birth weight infants: a systematic review and meta-analysis.

Authors:  Shunsuke Araki; Shin Kato; Fumihiko Namba; Erika Ota
Journal:  PLoS One       Date:  2018-11-29       Impact factor: 3.240

Review 4.  Evidence for the Management of Bronchopulmonary Dysplasia in Very Preterm Infants.

Authors:  Tobias Muehlbacher; Dirk Bassler; Manuel B Bryant
Journal:  Children (Basel)       Date:  2021-04-13

5.  Early Vitamin A Supplementation for Prevention of Short-Term Morbidity and Mortality in Very-Low-Birth-Weight Infants: A Systematic Review and Meta-Analysis.

Authors:  Yanxiu Ye; Xiaoyan Yang; Jing Zhao; Jianghua He; Xiaoming Xu; Jiao Li; Jing Shi; Dezhi Mu
Journal:  Front Pediatr       Date:  2022-04-07       Impact factor: 3.569

Review 6.  Role of Vitamin A in Mammary Gland Development and Lactation.

Authors:  M Teresa Cabezuelo; Rosa Zaragozá; Teresa Barber; Juan R Viña
Journal:  Nutrients       Date:  2019-12-27       Impact factor: 5.717

Review 7.  Supplemental Oxygen in the Newborn: Historical Perspective and Current Trends.

Authors:  Maxwell Mathias; Jill Chang; Marta Perez; Ola Saugstad
Journal:  Antioxidants (Basel)       Date:  2021-11-25
  7 in total

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