Literature DB >> 27670931

Expression of the insulinoma-associated 1 (insm1) gene in Xenopus laevis tadpole retina and brain.

Jennifer L Bosse1, Heithem M El-Hodiri2.   

Abstract

The insulinoma-associated 1 (insm1) gene is involved in the differentiation of several neuronal and endoderm derived cell types. insm1 is expressed in the retina and brain of several vertebrates including Xenopus laevis. We report the detailed expression pattern of insm1 in the X. laevis tadpole retina and brain. X. laevis insm1 is expressed in most of the ciliary marginal zone of the mature retina and the optic tectum, dorsal pallium, hypothalamus and preoptic areas of the developing tadpole brain. Overall, insm1 is expressed in regions of the tadpole brain and retina harboring populations of progenitor cells.
Copyright © 2016 Elsevier B.V. All rights reserved.

Entities:  

Keywords:  Ciliary marginal zone; Dorsal pallium; Hypothalamus; Optic tectum; Xenopus laevis; insm1

Mesh:

Substances:

Year:  2016        PMID: 27670931      PMCID: PMC5114149          DOI: 10.1016/j.gep.2016.09.004

Source DB:  PubMed          Journal:  Gene Expr Patterns        ISSN: 1567-133X            Impact factor:   1.224


  31 in total

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Authors:  Branden R Nelson; Byron H Hartman; Sean A Georgi; Michael S Lan; Thomas A Reh
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2.  The genetic sequence of retinal development in the ciliary margin of the Xenopus eye.

Authors:  M Perron; S Kanekar; M L Vetter; W A Harris
Journal:  Dev Biol       Date:  1998-07-15       Impact factor: 3.582

3.  Xotch, the Xenopus homolog of Drosophila notch.

Authors:  C Coffman; W Harris; C Kintner
Journal:  Science       Date:  1990-09-21       Impact factor: 47.728

4.  Targeted cytosine deaminase-uracil phosphoribosyl transferase suicide gene therapy induces small cell lung cancer-specific cytotoxicity and tumor growth delay.

Authors:  Camilla L Christensen; Torben Gjetting; Thomas T Poulsen; Frederik Cramer; Jack A Roth; Hans S Poulsen
Journal:  Clin Cancer Res       Date:  2010-04-06       Impact factor: 12.531

5.  A novel human insulinoma-associated cDNA, IA-1, encodes a protein with "zinc-finger" DNA-binding motifs.

Authors:  Y Goto; M G De Silva; A Toscani; B S Prabhakar; A L Notkins; M S Lan
Journal:  J Biol Chem       Date:  1992-07-25       Impact factor: 5.157

6.  Insulinoma-associated 1a (Insm1a) is required for photoreceptor differentiation in the zebrafish retina.

Authors:  Marie A Forbes-Osborne; Stephen G Wilson; Ann C Morris
Journal:  Dev Biol       Date:  2013-06-04       Impact factor: 3.582

7.  The insulinoma-associated 1: a novel promoter for targeted cancer gene therapy for small-cell lung cancer.

Authors:  N Pedersen; M W Pedersen; M S Lan; M B Breslin; H S Poulsen
Journal:  Cancer Gene Ther       Date:  2006-04       Impact factor: 5.987

8.  The Retinal Homeobox (Rx) gene is necessary for retinal regeneration.

Authors:  Reyna I Martinez-De Luna; Lisa E Kelly; Heithem M El-Hodiri
Journal:  Dev Biol       Date:  2011-02-17       Impact factor: 3.582

9.  Xenopus zinc finger transcription factor IA1 (Insm1) expression marks anteroventral noradrenergic neuron progenitors in Xenopus embryos.

Authors:  Damien Parlier; Ana Ariza; Fotini Christulia; Flavio Genco; Jessica Vanhomwegen; Sadia Kricha; Jacob Souopgui; Eric J Bellefroid
Journal:  Dev Dyn       Date:  2008-08       Impact factor: 3.780

10.  Insm1 (IA-1) is an essential component of the regulatory network that specifies monoaminergic neuronal phenotypes in the vertebrate hindbrain.

Authors:  John Jacob; Robert Storm; Diogo S Castro; Christopher Milton; Patrick Pla; François Guillemot; Carmen Birchmeier; James Briscoe
Journal:  Development       Date:  2009-07       Impact factor: 6.868

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