Literature DB >> 27670900

Correction: Specific contributions of the four voltage-sensing domains in L-type calcium channels to gating and modulation.

Bernhard E Flucher.   

Abstract

Entities:  

Year:  2016        PMID: 27670900      PMCID: PMC5037346          DOI: 10.1085/jgp.20161166309142016c

Source DB:  PubMed          Journal:  J Gen Physiol        ISSN: 0022-1295            Impact factor:   4.086


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Volume 148, No. 2, August 8, 2016. Pages 91–95. In the original version of this Commentary, the following text was included in the ninth paragraph: “Although a left shift of V1/2 upon coexpression of α2δ-1 has consistently been observed in past studies, the magnitude reported here is unprecedented. Even in earlier experiments from the Olcese laboratory, shifts of only −10 mV were reported (Platano et al., 2000). At this time, the reason for this unusually large voltage shift upon coexpression of α2δ-1 remains unknown.” After publication, the author noticed that a −50-mV shift of the voltage dependence of the tail currents in the presence of the α2δ-1 subunit, similar to that found in the paper of reference (Savalli et al., 2016), had been reported in the earlier study by Platano et al. (2000; Fig. 5 E). In contrast, the statement in our Commentary related to the shift of IV curves, which indeed is much smaller (−10 mV) than that determined from the tail currents (Platano et al., 2000; Fig. 1 C). Therefore, the sentences quoted above are in error and have been deleted from the HTML and PDF versions of the Commentary. As these sentences contained the only citation of Platano et al. (2000), this reference has also been removed. The error remains only in the print version.
  2 in total

1.  Expression of the alpha(2)delta subunit interferes with prepulse facilitation in cardiac L-type calcium channels.

Authors:  D Platano; N Qin; F Noceti; L Birnbaumer; E Stefani; R Olcese
Journal:  Biophys J       Date:  2000-06       Impact factor: 4.033

2.  The α2δ-1 subunit remodels CaV1.2 voltage sensors and allows Ca2+ influx at physiological membrane potentials.

Authors:  Nicoletta Savalli; Antonios Pantazis; Daniel Sigg; James N Weiss; Alan Neely; Riccardo Olcese
Journal:  J Gen Physiol       Date:  2016-08       Impact factor: 4.086

  2 in total

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