Literature DB >> 27668250

Aging vs. rejuvenation: reprogramming to iPSCs does not turn back the clock for somatic mitochondrial DNA mutations.

Carmen Lorenz1, Alessandro Prigione2.   

Abstract

Year:  2016        PMID： 27668250      PMCID： PMC5014851          DOI： 10.21037/sci.2016.08.09

Source DB:  PubMed          Journal:  Stem Cell Investig        ISSN： 2306-9759


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  10 in total

1.  Metabolic rescue in pluripotent cells from patients with mtDNA disease.

Authors:  Hong Ma; Clifford D L Folmes; Jun Wu; Robert Morey; Sergio Mora-Castilla; Alejandro Ocampo; Li Ma; Joanna Poulton; Xinjian Wang; Riffat Ahmed; Eunju Kang; Yeonmi Lee; Tomonari Hayama; Ying Li; Crystal Van Dyken; Nuria Marti Gutierrez; Rebecca Tippner-Hedges; Amy Koski; Nargiz Mitalipov; Paula Amato; Don P Wolf; Taosheng Huang; Andre Terzic; Louise C Laurent; Juan Carlos Izpisua Belmonte; Shoukhrat Mitalipov
Journal:  Nature       Date:  2015-07-15       Impact factor: 49.962

2.  Stem cells: The dark side of induced pluripotency.

Authors:  Martin F Pera
Journal:  Nature       Date:  2011-03-03       Impact factor: 49.962

3.  Human induced pluripotent stem cells harbor homoplasmic and heteroplasmic mitochondrial DNA mutations while maintaining human embryonic stem cell-like metabolic reprogramming.

Authors:  Alessandro Prigione; Björn Lichtner; Heiner Kuhl; Eduard A Struys; Mirjam Wamelink; Hans Lehrach; Markus Ralser; Bernd Timmermann; James Adjaye
Journal:  Stem Cells       Date:  2011-09       Impact factor: 6.277

4.  Tissue- and cell-type-specific manifestations of heteroplasmic mtDNA 3243A>G mutation in human induced pluripotent stem cell-derived disease model.

Authors:  Riikka H Hämäläinen; Tuula Manninen; Hanna Koivumäki; Mikhail Kislin; Timo Otonkoski; Anu Suomalainen
Journal:  Proc Natl Acad Sci U S A       Date:  2013-09-03       Impact factor: 11.205

5.  Age-Related Accumulation of Somatic Mitochondrial DNA Mutations in Adult-Derived Human iPSCs.

Authors:  Eunju Kang; Xinjian Wang; Rebecca Tippner-Hedges; Hong Ma; Clifford D L Folmes; Nuria Marti Gutierrez; Yeonmi Lee; Crystal Van Dyken; Riffat Ahmed; Ying Li; Amy Koski; Tomonari Hayama; Shiyu Luo; Cary O Harding; Paula Amato; Jeffrey Jensen; David Battaglia; David Lee; Diana Wu; Andre Terzic; Don P Wolf; Taosheng Huang; Shoukhrat Mitalipov
Journal:  Cell Stem Cell       Date:  2016-04-14       Impact factor: 24.633

6.  Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors.

Authors:  Kazutoshi Takahashi; Shinya Yamanaka
Journal:  Cell       Date:  2006-08-10       Impact factor: 41.582

Review 7.  Human mitochondrial DNA: roles of inherited and somatic mutations.

Authors:  Eric A Schon; Salvatore DiMauro; Michio Hirano
Journal:  Nat Rev Genet       Date:  2012-12       Impact factor: 53.242

8.  Disease-causing mitochondrial heteroplasmy segregated within induced pluripotent stem cell clones derived from a patient with MELAS.

Authors:  Clifford D L Folmes; Almudena Martinez-Fernandez; Ester Perales-Clemente; Xing Li; Amber McDonald; Devin Oglesbee; Sybil C Hrstka; Carmen Perez-Terzic; Andre Terzic; Timothy J Nelson
Journal:  Stem Cells       Date:  2013-07       Impact factor: 6.277

9.  A pattern of accumulation of a somatic deletion of mitochondrial DNA in aging human tissues.

Authors:  G A Cortopassi; D Shibata; N W Soong; N Arnheim
Journal:  Proc Natl Acad Sci U S A       Date:  1992-08-15       Impact factor: 11.205

10.  Mitochondrial-associated cell death mechanisms are reset to an embryonic-like state in aged donor-derived iPS cells harboring chromosomal aberrations.

Authors:  Alessandro Prigione; Amir M Hossini; Björn Lichtner; Akdes Serin; Beatrix Fauler; Matthias Megges; Rudi Lurz; Hans Lehrach; Eugenia Makrantonaki; Christos C Zouboulis; James Adjaye
Journal:  PLoS One       Date:  2011-11-14       Impact factor: 3.240
  10 in total
  1 in total

1.  The relevance of mitochondrial DNA variants fluctuation during reprogramming and neuronal differentiation of human iPSCs.

Authors:  Flavia Palombo; Camille Peron; Leonardo Caporali; Angelo Iannielli; Alessandra Maresca; Ivano Di Meo; Claudio Fiorini; Alice Segnali; Francesca L Sciacca; Ambra Rizzo; Sonia Levi; Anu Suomalainen; Alessandro Prigione; Vania Broccoli; Valerio Carelli; Valeria Tiranti
Journal:  Stem Cell Reports       Date:  2021-07-29       Impact factor: 7.765
  1 in total

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