AIM: To analyze the outcomes of transanal endoscopic microsurgery (TEM) in the treatment of rare rectal condition like mesenchymal tumors, condylomas, endometriosis and melanoma. METHODS: We retrospectively reviewed a twenty-three years database. Fifty-two patients were enrolled in this study. The lesions were considered suitable for TEM if they were within 20 cm from the anus. All of them underwent an accurate preoperative workup consisting in clinical examination, total colonoscopy with biopsies, endoscopic ultrasonography, and pelvic computerized tomography or pelvic magnetic resonance imaging. Operative time, intraoperative complications, rate of conversion, tumor size, postoperative morbidity, mortality, the length of hospital stay, local and distant recurrence were analyzed. RESULTS: Among the 1328 patients treated by TEM in our department, the 52 patients with rectal abnormalities other than adenoma or adenocarcinoma represented 4.4%. There were 30 males (57.7%) and 22 females (42.3%). Mean age was 55 years (median = 60, range = 24-78). This series included 14 (26.9%) gastrointestinal stromal tumors, 21 neuroendocrine tumors (40.4%), 1 ganglioneuroma (1.9%), 2 solitary ulcers in the rectum (3.8%), 6 cases of rectal endometriosis (11.5%), 6 cases of rectal condylomatosis (11.5%) and 2 rectal melanomas (3.8%). Mean lesion diameter was 2.7 cm (median: 4, range: 0.4-8). Mean distance from the anal verge was 9.5 cm (median: 10, range: 4-15). One patient operated for rectal melanoma developed distant metastases and died two years after the operation. We experienced 2 local recurrences (3.8%) with an overall survival equal to 97.6% (95%CI: 95%-99%) at the end of follow-up and a disease free survival of 98% (95%CI: 96%-99%). CONCLUSION: We could conclude that TEM is an important therapeutical option for rectal rare conditions.
AIM: To analyze the outcomes of transanal endoscopic microsurgery (TEM) in the treatment of rare rectal condition like mesenchymal tumors, condylomas, endometriosis and melanoma. METHODS: We retrospectively reviewed a twenty-three years database. Fifty-two patients were enrolled in this study. The lesions were considered suitable for TEM if they were within 20 cm from the anus. All of them underwent an accurate preoperative workup consisting in clinical examination, total colonoscopy with biopsies, endoscopic ultrasonography, and pelvic computerized tomography or pelvic magnetic resonance imaging. Operative time, intraoperative complications, rate of conversion, tumor size, postoperative morbidity, mortality, the length of hospital stay, local and distant recurrence were analyzed. RESULTS: Among the 1328 patients treated by TEM in our department, the 52 patients with rectal abnormalities other than adenoma or adenocarcinoma represented 4.4%. There were 30 males (57.7%) and 22 females (42.3%). Mean age was 55 years (median = 60, range = 24-78). This series included 14 (26.9%) gastrointestinal stromal tumors, 21 neuroendocrine tumors (40.4%), 1 ganglioneuroma (1.9%), 2 solitary ulcers in the rectum (3.8%), 6 cases of rectal endometriosis (11.5%), 6 cases of rectal condylomatosis (11.5%) and 2 rectal melanomas (3.8%). Mean lesion diameter was 2.7 cm (median: 4, range: 0.4-8). Mean distance from the anal verge was 9.5 cm (median: 10, range: 4-15). One patient operated for rectal melanoma developed distant metastases and died two years after the operation. We experienced 2 local recurrences (3.8%) with an overall survival equal to 97.6% (95%CI: 95%-99%) at the end of follow-up and a disease free survival of 98% (95%CI: 96%-99%). CONCLUSION: We could conclude that TEM is an important therapeutical option for rectal rare conditions.
Authors: R M Helewa; A N Rajaee; I Raiche; L Williams; M Paquin-Gobeil; R P Boushey; H Moloo Journal: Colorectal Dis Date: 2016-11 Impact factor: 3.788
Authors: Joon Han Jeon; Dae Young Cheung; Seong Jin Lee; Hyun Jin Kim; Hye Kang Kim; Hyung Jun Cho; In Kyu Lee; Jin Il Kim; Soo-Heon Park; Jae Kwang Kim Journal: Dig Endosc Date: 2014-01-22 Impact factor: 7.559
Authors: Soung Min Jeon; Jin Ha Lee; Sung Pil Hong; Tae Il Kim; Won Ho Kim; Jae Hee Cheon Journal: Gastrointest Endosc Date: 2011-02-12 Impact factor: 9.427
Authors: Matthew T Ballo; Jeffrey E Gershenwald; Gunar K Zagars; Jeffrey E Lee; Paul F Mansfield; Eric A Strom; Agop Y Bedikian; Kevin B S Kim; Nicholas E Papadopoulos; Victor G Prieto; Merrick I Ross Journal: J Clin Oncol Date: 2002-12-01 Impact factor: 44.544
Authors: Imran Hassan; Y Nancy You; Eric J Dozois; Roman Shayyan; Thomas C Smyrk; Scott H Okuno; John H Donohue Journal: Dis Colon Rectum Date: 2006-05 Impact factor: 4.585
Authors: Camilla Gallo; Roberta Elisa Rossi; Federica Cavalcoli; Federico Barbaro; Ivo Boškoski; Pietro Invernizzi; Sara Massironi Journal: World J Gastroenterol Date: 2022-03-21 Impact factor: 5.742
Authors: Markus Brand; Stanislaus Reimer; Joachim Reibetanz; Sven Flemming; Marko Kornmann; Alexander Meining Journal: Int J Colorectal Dis Date: 2020-11-19 Impact factor: 2.571