Valerie Wing Yu Wong1, Daniel Yee Tak Fong2, Kris Yuet Wan Lok3, Janet Yuen Ha Wong4, Chu Sing5, Alice Yin-Yin Choi6, Carol Yuet Sheung Yuen7, Marie Tarrant8. 1. School of Nursing, The University of Hong Kong, 21 Sassoon Road, Pokfulam, Hong Kong. Electronic address: valywong@gmail.com. 2. School of Nursing, The University of Hong Kong, 21 Sassoon Road, Pokfulam, Hong Kong. Electronic address: dytfong@hku.hk. 3. School of Nursing, The University of Hong Kong, 21 Sassoon Road, Pokfulam, Hong Kong. Electronic address: krislok@hku.hk. 4. School of Nursing, The University of Hong Kong, 21 Sassoon Road, Pokfulam, Hong Kong. Electronic address: janetyh@hku.hk. 5. Dept. of Obstetrics and Gynaecology, Kwong Wah Hospital, 25 Waterloo Road, Kowloon, Hong Kong. Electronic address: singc@ha.org.hk. 6. Dept. of Obstetrics and Gynaecology, Queen Mary Hospital, 102 Pokfulam Road, Pokfulam, Hong Kong. Electronic address: choiyy@ha.org.hk. 7. School of Nursing, The University of Hong Kong, 21 Sassoon Road, Pokfulam, Hong Kong. Electronic address: carol_iou@hotmail.com. 8. School of Nursing, The University of Hong Kong, 21 Sassoon Road, Pokfulam, Hong Kong; School of Nursing, University of British Columbia, 3333 University Way, Kelowna, British Columbia, Canada. Electronic address: tarrantm@hku.hk.
Abstract
BACKGROUND: Although pregnant women are the highest priority group for seasonal influenza vaccination, maternal influenza vaccination rates remain suboptimal. The purpose of this study was to evaluate the effect of a brief education intervention on maternal influenza vaccine uptake. METHODS: During the 2013-14 and 2014-15 influenza seasons, we recruited 321 pregnant women from the antenatal clinics of 4 out of 8 public hospitals in Hong Kong with obstetric services. Hospitals were geographically dispersed and provided services to pregnant women with variable socioeconomic backgrounds. Participants were randomized to receive either standard antenatal care or brief one-to-one education. Participants received telephone follow-up at 2 weeks postpartum. The primary study outcome was self-reported receipt of influenza vaccination during pregnancy. The secondary outcomes were the proportion of participants who initiated discussion about influenza vaccination with a health care professional and the proportion of participants who attempted to get vaccinated. RESULTS: Compared with participants who received standard care, the vaccination rate was higher among participants who received brief education (21.1% vs. 10%; p=0.006). More participants in the education group initiated discussion about influenza vaccination with their HCP (19.9% vs. 13.1%; p=0.10), but the difference was not statistically significant. Of participants who did not receive the influenza vaccine (n=271), 45 attempted to get vaccinated. A significantly higher proportion of participants who attempted to get vaccinated were in the intervention group (82.2% vs. 17.8%; p<0.001). If participants who had attempted vaccination had received the vaccine, vaccination rates would have been substantially higher (44.1% vs. 15%; p<0.001). Twenty-six participants were advised against influenza vaccination by a healthcare professional, including general practitioners, obstetricians, and nurses. CONCLUSION: Although brief education was effective in improving vaccination uptake among pregnant women, overall vaccination rates remain suboptimal. Multicomponent approaches, including positive vaccination recommendations by healthcare professionals, are needed to promote maternal influenza vaccination. CLINICAL TRIAL REGISTRATION: www.clinicaltrials.gov (NCT01772901).
RCT Entities:
BACKGROUND: Although pregnant women are the highest priority group for seasonal influenza vaccination, maternal influenza vaccination rates remain suboptimal. The purpose of this study was to evaluate the effect of a brief education intervention on maternal influenza vaccine uptake. METHODS: During the 2013-14 and 2014-15 influenza seasons, we recruited 321 pregnant women from the antenatal clinics of 4 out of 8 public hospitals in Hong Kong with obstetric services. Hospitals were geographically dispersed and provided services to pregnant women with variable socioeconomic backgrounds. Participants were randomized to receive either standard antenatal care or brief one-to-one education. Participants received telephone follow-up at 2 weeks postpartum. The primary study outcome was self-reported receipt of influenza vaccination during pregnancy. The secondary outcomes were the proportion of participants who initiated discussion about influenza vaccination with a health care professional and the proportion of participants who attempted to get vaccinated. RESULTS: Compared with participants who received standard care, the vaccination rate was higher among participants who received brief education (21.1% vs. 10%; p=0.006). More participants in the education group initiated discussion about influenza vaccination with their HCP (19.9% vs. 13.1%; p=0.10), but the difference was not statistically significant. Of participants who did not receive the influenza vaccine (n=271), 45 attempted to get vaccinated. A significantly higher proportion of participants who attempted to get vaccinated were in the intervention group (82.2% vs. 17.8%; p<0.001). If participants who had attempted vaccination had received the vaccine, vaccination rates would have been substantially higher (44.1% vs. 15%; p<0.001). Twenty-six participants were advised against influenza vaccination by a healthcare professional, including general practitioners, obstetricians, and nurses. CONCLUSION: Although brief education was effective in improving vaccination uptake among pregnant women, overall vaccination rates remain suboptimal. Multicomponent approaches, including positive vaccination recommendations by healthcare professionals, are needed to promote maternal influenza vaccination. CLINICAL TRIAL REGISTRATION: www.clinicaltrials.gov (NCT01772901).
Authors: Mallory K Ellingson; Matthew Z Dudley; Rupali J Limaye; Daniel A Salmon; Sean T O'Leary; Saad B Omer Journal: Expert Rev Vaccines Date: 2019-01-28 Impact factor: 5.217