Literature DB >> 2766649

Are certain HLA haplotypes responsible for low testosterone levels in males?

W Ollier1, T Spector, A Silman, L Perry, J Ord, W Thomson, H Festenstein.   

Abstract

The level of testosterone on 138 HLA typed healthy males and 71 male rheumatoid arthritis patients were analysed. HLA-B15 was associated with a lower mean serum testosterone level in males than any other tissue type. This was observed in both the normal and RA groups.

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Year:  1989        PMID: 2766649

Source DB:  PubMed          Journal:  Dis Markers        ISSN: 0278-0240            Impact factor:   3.434


  12 in total

1.  HLA markers, hormones, and disease.

Authors:  W H James
Journal:  J Med Genet       Date:  1991-05       Impact factor: 6.318

2.  Role of androgens in the aetiology of rheumatoid arthritis.

Authors:  P Brennan; A Silman
Journal:  Ann Rheum Dis       Date:  1996-06       Impact factor: 19.103

Review 3.  Sex ratios and hormones in HLA related rheumatic diseases.

Authors:  W H James
Journal:  Ann Rheum Dis       Date:  1991-06       Impact factor: 19.103

4.  Why the gender difference in susceptibility to rheumatoid arthritis?

Authors:  P Brennan; A Silman
Journal:  Ann Rheum Dis       Date:  1995-09       Impact factor: 19.103

5.  Might patients with HLA-B27 related diseases benefit from antiandrogenic treatment?

Authors:  W H James
Journal:  Ann Rheum Dis       Date:  1995-06       Impact factor: 19.103

6.  HLA-B35 upregulates endothelin-1 and downregulates endothelial nitric oxide synthase via endoplasmic reticulum stress response in endothelial cells.

Authors:  Stefania Lenna; Danyelle M Townsend; Filemon K Tan; Bagrat Kapanadze; Malgorzata Markiewicz; Maria Trojanowska; Raffaella Scorza
Journal:  J Immunol       Date:  2010-03-24       Impact factor: 5.422

7.  Polymorphic CAG repeats of the androgen receptor gene and rheumatoid arthritis.

Authors:  T Kawasaki; T Ushiyama; H Ueyama; K Inoue; K Mori; I Ohkubo; S Hukuda
Journal:  Ann Rheum Dis       Date:  1999-08       Impact factor: 19.103

8.  Rheumatoid arthritis, the contraceptive pill, and androgens.

Authors:  W H James
Journal:  Ann Rheum Dis       Date:  1993-06       Impact factor: 19.103

9.  Rheumatoid arthritis, HLA identity, and age at menarche.

Authors:  C M Deighton; H Sykes; D J Walker
Journal:  Ann Rheum Dis       Date:  1993-05       Impact factor: 19.103

10.  Serum androgen-anabolic hormones and the risk of rheumatoid arthritis.

Authors:  R Heikkilä; K Aho; M Heliövaara; P Knekt; A Reunanen; A Aromaa; A Leino; T Palosuo
Journal:  Ann Rheum Dis       Date:  1998-05       Impact factor: 19.103

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