Literature DB >> 2766579

Defective antibody-dependent tumour cell lysis by neutrophils from cancer patients.

F Dallegri1, A Ballestrero, L Ottonello, F Patrone.   

Abstract

Neutrophil antibody-dependent cellular cytotoxicity (ADCC) against Raji target cells was studied in 32 patients with lung or gastro-intestinal carcinoma and 25 healthy controls. Seventeen of the patients (53%) had defective ADCC. Moreover, neutrophils obtained from patients with defective ADCC were found to bind IgG-coated target cells normally. Thus, the defect responsible for the impaired lysis appears to be distal to the Fc receptor (FcR)-mediated target cell binding by neutrophils.

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Year:  1989        PMID： 2766579      PMCID： PMC1541921     

Source DB:  PubMed          Journal:  Clin Exp Immunol        ISSN： 0009-9104            Impact factor:   4.330


  10 in total

1.  Relationship between antibody-dependent tumour cell lysis and primary granule exocytosis by human neutrophils.

Authors:  F Dallegri; G Frumento; A Ballestrero; R Goretti; F Patrone
Journal:  Clin Exp Immunol       Date:  1987-11       Impact factor: 4.330

Review 2.  The cytotoxic action of neutrophils on mammalian cells in vitro.

Authors:  E L Becker
Journal:  Prog Allergy       Date:  1988

3.  Reduced membrane receptor activity of polymorphonuclear leucocytes of cancer patients.

Authors:  T Umeda; H Yokoyama; K Kobayashi; H Akaza; T Niijima
Journal:  Cell Mol Biol Incl Cyto Enzymol       Date:  1980

4.  A test of granulocyte membrane integrity and phagocytic function.

Authors:  F Dankberg; M D Persidsky
Journal:  Cryobiology       Date:  1976-08       Impact factor: 2.487

5.  Phagocyte-generated oxygen metabolites and cellular injury.

Authors:  S J Weiss; A F LoBuglio
Journal:  Lab Invest       Date:  1982-07       Impact factor: 5.662

6.  Tumor cells cytotoxicity by granulocytes from peripheral blood of tumor-bearing mice.

Authors:  B Fisher; E A Saffer
Journal:  J Natl Cancer Inst       Date:  1978-03       Impact factor: 13.506

7.  A comparison of the cytotoxic potential in polymorphonuclear leukocytes obtained from normal donors and cancer patients.

Authors:  D J Cameron
Journal:  Clin Immunol Immunopathol       Date:  1983-07

8.  Antibody-dependent tumour cytolysis by human neutrophils: effect of synthetic serine esterase inhibitors and substrates.

Authors:  F Dallegri; G Frumento; A Ballestrero; R Goretti; A Torresin; F Patrone
Journal:  Immunology       Date:  1987-11       Impact factor: 7.397

9.  Serum-associated inhibition of neutrophil Fc receptors in cancer patients.

Authors:  F Patrone; F Dallegri; A Gremmo; E Bonvini; P Migliorini; S Cantarella; M Ferrarini; C Sacchetti
Journal:  J Natl Cancer Inst       Date:  1981-10       Impact factor: 13.506

10.  Antibody-dependent killing of tumor cells by polymorphonuclear leukocytes. Involvement of oxidative and nonoxidative mechanisms.

Authors:  F Dallegri; F Patrone; G Frumento; C Sacchetti
Journal:  J Natl Cancer Inst       Date:  1984-08       Impact factor: 13.506
  10 in total
  4 in total

1.  Anti-GD2 antibody with GM-CSF, interleukin-2, and isotretinoin for neuroblastoma.

Authors:  Alice L Yu; Andrew L Gilman; M Fevzi Ozkaynak; Wendy B London; Susan G Kreissman; Helen X Chen; Malcolm Smith; Barry Anderson; Judith G Villablanca; Katherine K Matthay; Hiro Shimada; Stephan A Grupp; Robert Seeger; C Patrick Reynolds; Allen Buxton; Ralph A Reisfeld; Steven D Gillies; Susan L Cohn; John M Maris; Paul M Sondel
Journal:  N Engl J Med       Date:  2010-09-30       Impact factor: 91.245

2.  An important role for granulocytes in the thermal regulation of colon tumor growth.

Authors:  Julie R Ostberg; Bradley R Ertel; Julie A Lanphere
Journal:  Immunol Invest       Date:  2005       Impact factor: 3.657

3.  Tumour cell lines HT-29 and FaDu produce proinflammatory cytokines and activate neutrophils in vitro: possible applications for neutrophil-based antitumour treatment.

Authors:  Antonio Brú; Juan-Carlos Souto; Sonia Alcolea; Rosa Antón; Angel Remacha; Mercedes Camacho; Marta Soler; Isabel Brú; Amelia Porres; Luis Vila
Journal:  Mediators Inflamm       Date:  2010-02-11       Impact factor: 4.711

Review 4.  Biointerface engineering nanoplatforms for cancer-targeted drug delivery.

Authors:  Huaiyu Zhang; Shujun Dong; Zhongmin Li; Xiangru Feng; Weiguo Xu; Catrina Mae S Tulinao; Yang Jiang; Jianxun Ding
Journal:  Asian J Pharm Sci       Date:  2019-12-30       Impact factor: 6.598
  4 in total

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