| Literature DB >> 27665598 |
Zhenjiang Zech Xu1,2, David H Mathews3,4,5.
Abstract
Experimental probing data can be used to improve the accuracy of RNA secondary structure prediction. The software package RNAstructure can take advantage of enzymatic cleavage data, FMN cleavage data, traditional chemical modification reactivity data, and SHAPE reactivity data for secondary structure modeling. This chapter provides protocols for using experimental probing data with RNAstructure to restrain or constrain RNA secondary structure prediction.Entities:
Keywords: Chemical modification data; RNA structure prediction; SHAPE; Thermodynamics
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Year: 2016 PMID： 27665598 DOI： 10.1007/978-1-4939-6433-8_10
Source DB: PubMed Journal: Methods Mol Biol ISSN： 1064-3745