Literature DB >> 27664204

The definition of IVM is clear-variations need defining.

Michel De Vos1, Johan Smitz2, Jeremy G Thompson3, Robert B Gilchrist4.   

Abstract

Oocyte in vitro maturation (IVM) is currently defined as the maturation in vitro of immature cumulus-oocyte complexes collected from antral follicles. This is the original definition as first described by Pincus and Enzmann and then by Edwards many decades ago, and this clear and unambiguous definition has served us well ever since. In an attempt to clarify apparent differences among clinicians, the following revised definition of IVM was recently proposed: 'The retrieval of oocytes from small and intermediate sized follicles in an ovary before the largest follicle has surpassed 13 mm in mean diameter'. As such, this proposed definition should encompass the use of hCG triggering. To change the clear and long-serving definition of IVM to fit varying clinical practices requires a compelling justification based on solid scientific and clinical grounds. We are of the opinion that the proposed revised definition of IVM is counterintuitive as it includes protocols that are intended to mature oocytes in vivo The proposed definitions are cumbersome and indeed further complicate the situation. It is not scientifically rational to base the definition on follicular size, and the definition ignores the vast corporate knowledge acquired from the many decades and >6000 publications in animal research that universally practices IVM as per the existing definition. Furthermore, such a definition can lead to false results in interpreting the follow-up of children conceived using IVM. Hence, we see no rationale to change the existing definition of IVM. However, we agree that variations on IVM require alternative nomenclature-these definitions need to be intuitive and need to clearly distinguish themselves from the existing long-standing definition of IVM. This would help to clarify the recent confusion within the clinical ART community as to what is and what is not, IVM.
© The Author 2016. Published by Oxford University Press on behalf of the European Society of Human Reproduction and Embryology. All rights reserved. For Permissions, please email: journals.permissions@oup.com.

Entities:  

Keywords:  ART; FSH; IVF; cumulus–oocyte complex; definition; follicle; hCG; in vitro maturation

Mesh:

Year:  2016        PMID: 27664204     DOI: 10.1093/humrep/dew208

Source DB:  PubMed          Journal:  Hum Reprod        ISSN: 0268-1161            Impact factor:   6.918


  19 in total

Review 1.  Novel Concepts for Inducing Final Oocyte Maturation in In Vitro Fertilization Treatment.

Authors:  Ali Abbara; Sophie A Clarke; Waljit S Dhillo
Journal:  Endocr Rev       Date:  2018-10-01       Impact factor: 19.871

Review 2.  Vitrification of human immature oocytes before and after in vitro maturation: a review.

Authors:  Mohammad Ali Khalili; Abbas Shahedi; Sareh Ashourzadeh; Stefania Annarita Nottola; Guido Macchiarelli; Maria Grazia Palmerini
Journal:  J Assist Reprod Genet       Date:  2017-08-18       Impact factor: 3.412

Review 3.  Can peri-ovulatory putrescine supplementation improve egg quality in older infertile women?

Authors:  Yong Tao; Alina Tartia; Maralee Lawson; Mary B Zelinski; Wei Wu; Jia-Yin Liu; Johan Smitz; Marie-Claude Léveillé; Arthur Leader; Hongmei Wang; Timothy Ramsay; X Johné Liu
Journal:  J Assist Reprod Genet       Date:  2018-11-22       Impact factor: 3.412

4.  The effect of short-term exposure of cumulus-oocyte complexes to in vitro maturation medium on yield of mature oocytes and usable embryos in stimulated cycles.

Authors:  C R Sacha; D J Kaser; L V Farland; S Srouji; S A Missmer; C Racowsky
Journal:  J Assist Reprod Genet       Date:  2018-03-14       Impact factor: 3.412

5.  Effect of cumulin and super-GDF9 in standard and biphasic mouse IVM.

Authors:  Nazli Akin; Dulama Richani; Xiuhua Liao; Yiqing Zhao; Anamaria-Cristina Herta; Katy Billooye; William A Stocker; David G Mottershead; Craig A Harrison; Johan Smitz; Ellen Anckaert; Robert B Gilchrist
Journal:  J Assist Reprod Genet       Date:  2022-01-04       Impact factor: 3.412

6.  The time is ripe for oocyte in vitro maturation.

Authors:  Carlos E Plancha; Patrícia Rodrigues; Mónica Marques; Joana M Almeida; Paulo Navarro-Costa
Journal:  J Assist Reprod Genet       Date:  2021-05-08       Impact factor: 3.412

7.  Live births after in vitro maturation of oocytes in women who had suffered adnexal torsion and unilateral oophorectomy following conventional ovarian stimulation.

Authors:  Dóra Vesztergom; Ingrid Segers; Linde Mostinckx; Christophe Blockeel; Michel De Vos
Journal:  J Assist Reprod Genet       Date:  2021-04-07       Impact factor: 3.357

8.  The live birth in a woman with resistant ovary syndrome after in vitro oocyte maturation and preimplantation genetic testing for aneuploidy.

Authors:  Nikolay Valerievich Kornilov; Marina Nikolaevna Pavlova; Pavel Pavlovich Yakovlev
Journal:  J Assist Reprod Genet       Date:  2021-01-26       Impact factor: 3.357

Review 9.  Perspectives on the development and future of oocyte IVM in clinical practice.

Authors:  Michel De Vos; Michaël Grynberg; Tuong M Ho; Ye Yuan; David F Albertini; Robert B Gilchrist
Journal:  J Assist Reprod Genet       Date:  2021-07-03       Impact factor: 3.412

Review 10.  The Improvement and Clinical Application of Human Oocyte In Vitro Maturation (IVM).

Authors:  Xueqi Gong; Hemei Li; Yiqing Zhao
Journal:  Reprod Sci       Date:  2021-06-02       Impact factor: 2.924

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