Literature DB >> 27663662

The power of OMICs.

Igor Stagljar1.   

Abstract

Over the past two decades, the field of systems biology, which encompasses the numerous, widely popular "OMICs" approaches, has driven many significant advances in biomedical research, enabling researchers to generate huge datasets at multiple levels of biological organization. Despite such successes, some scientists still think that "OMICs"-based research introduces a lot of chaos into the biomedical field and claim that the resultant data are often not reproducible and do not reveal deep mechanistic aspects of biological processes. In this editorial, I argue the following: first, that "OMICs" technologies have improved significantly to yield much better datasets; and second, that follow-up studies on components identified in "OMICs" analyses have yielded many valuable biological insights.
Copyright © 2016 Elsevier Inc. All rights reserved.

Mesh:

Year:  2016        PMID: 27663662     DOI: 10.1016/j.bbrc.2016.09.095

Source DB:  PubMed          Journal:  Biochem Biophys Res Commun        ISSN: 0006-291X            Impact factor:   3.575


  5 in total

1.  A power law distribution of metabolite abundance levels in mice regardless of the time and spatial scale of analysis.

Authors:  Shumpei Sato; Makoto Horikawa; Takeshi Kondo; Tomohito Sato; Mitsutoshi Setou
Journal:  Sci Rep       Date:  2018-07-09       Impact factor: 4.379

2.  Combined transcriptomic and lipidomic analysis reveals aberrant lipid metabolism in central nervous system hemangioblastomas.

Authors:  Qiguang Wang; Wenke Liu; Si Zhang; Zuoyu Liang; Linhong Jiang; Aiqin Xue; Xiaobo Cen; Qian Bu
Journal:  Sci Rep       Date:  2021-01-14       Impact factor: 4.379

Review 3.  Linking Multi-Omics to Wheat Resistance Types to Fusarium Head Blight to Reveal the Underlying Mechanisms.

Authors:  Fan Wu; Yao Zhou; Yingying Shen; Zhengxi Sun; Lei Li; Tao Li
Journal:  Int J Mol Sci       Date:  2022-02-18       Impact factor: 5.923

4.  Multi-omics & pathway analysis identify potential roles for tumor N-acetyl aspartate accumulation in murine models of castration-resistant prostate cancer.

Authors:  Mark J Salji; Arnaud Blomme; J Henry M Däbritz; Peter Repiscak; Sergio Lilla; Rachana Patel; David Sumpton; Niels J F van den Broek; Ronan Daly; Sara Zanivan; Hing Y Leung
Journal:  iScience       Date:  2022-03-11

5.  Split Intein-Mediated Protein Ligation for detecting protein-protein interactions and their inhibition.

Authors:  Zhong Yao; Farzaneh Aboualizadeh; Jason Kroll; Indira Akula; Jamie Snider; Anna Lyakisheva; Priscilla Tang; Max Kotlyar; Igor Jurisica; Mike Boxem; Igor Stagljar
Journal:  Nat Commun       Date:  2020-05-15       Impact factor: 14.919

  5 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.