Literature DB >> 27663491

Clinical spectrum of yellow phosphorous poisoning in a tertiary care centre in South India: a case series.

Ajay Kumar Mishra1, Nathaniel Samson Devakiruba1, Sudha Jasmine2, Sowmya Sathyendra3, Anand Zachariah4, Ramya Iyadurai5.   

Abstract

Rodenticides such as yellow phosphorus are highly toxic compounds which are commonly used for pest control. Reports of yellow phosphorus poisoning from tropical nations is scanty. In this retrospective study, we report the clinical features, mortality and predictors of mortality among nine patients at a tertiary care centre in south India. Yellow phosphorus consumption was common among a younger age group of patients. The mean duration of presentation after consumption was five days. The most common clinical manifestations seen were abdominal pain and vomiting followed by a depressed sensorium. Features of acute liver failure including coagulopathy were seen in all patients. Despite all patients receiving supportive therapy, a poor outcome or death resulted in the majority. Early referral to a tertiary care centre, meticulous monitoring and supportive measures are key elements of patient management as there are no specific antidotes available at present. Increase in public and physician awareness to the toxin and implementation of preventive policies is of utmost importance.

Entities:  

Keywords:  Yellow phosphorus; hepatic failure; outcome; predictors; rodenticide poison

Mesh:

Substances:

Year:  2016        PMID: 27663491     DOI: 10.1177/0049475516668986

Source DB:  PubMed          Journal:  Trop Doct        ISSN: 0049-4755            Impact factor:   0.731


  6 in total

1.  Acute liver failure secondary to yellow phosphorus rodenticide poisoning: Outcomes at a center with dedicated liver intensive care and transplant unit.

Authors:  Ravi Mohanka; Prashantha Rao; Mitul Shah; Amit Gupte; Vinayak Nikam; Mihir Vohra; Ruhi Kohli; Anurag Shrimal; Ankush Golhar; Ameya Panchwagh; Saurabh Kamath; Akash Shukla; Priyesh Patel; Somnath Chattopadhyay; Gaurav Chaubal; Yasmin Shaikh; Vidhi Dedhia; Shivali S Sarmalkar; Ravikiran Maghade; Kavita Shinde; Priyanka Bhilare; Rohini Nalawade; Jacob As; Samir Shah
Journal:  J Clin Exp Hepatol       Date:  2020-10-08

2.  Rodenticide (Yellow Phosphorus Poison)-Induced Hepatotoxicity in India: Constraints During Management.

Authors:  Chundamannil E Eapen; Jayanthi Venkataraman
Journal:  J Clin Exp Hepatol       Date:  2021-04-30

3.  Rodenticide Poisoning: Critical Appraisal of Patients at a Tertiary Care Center.

Authors:  Shivkumar Gopalakrishnan; Sangeetha Kandasamy; Ramya Iyyadurai
Journal:  Indian J Crit Care Med       Date:  2020-05

4.  Outcome of Plasma Exchange in Acute Liver Failure due to Yellow Phosphorus Poisoning: A Single-center Experience.

Authors:  Srivatsa Angraje; Manikantan Sekar; Biswajit Mishra; Jayakumar Matcha
Journal:  Indian J Crit Care Med       Date:  2021-09

5.  Importance of pesticides for lethal poisoning in India during 1999 to 2018: a systematic review.

Authors:  Ayanthi Karunarathne; Ashish Bhalla; Aastha Sethi; Uditha Perera; Michael Eddleston
Journal:  BMC Public Health       Date:  2021-07-22       Impact factor: 3.295

6.  Liver Transplantation Society of India Guidelines for the Management of Acute Liver Injury Secondary to Yellow Phosphorus-Containing Rodenticide Poisoning Using the Modified Delphi Technique of Consensus Development.

Authors:  Mettu S Reddy; Akila Rajakumar; Johns S Mathew; L Venkatakrishnan; Dinesh Jothimani; S Sudhindran; Mathew Jacob; Krishnasamy Narayanasamy; Radhika Venugopal; Ravi Mohanka; Ilankumaran Kaliamoorthy; Joy Varghese; Charles Panackel; Zubair Mohamed; Mukul Vij; Deepti Sachan; V V Pillay; Sanjiv Saigal; Radhakrishna Dhiman; Arvinder S Soin; Subhash Gupta; Julia Wendon; Mohamed Rela; Shiv K Sarin
Journal:  J Clin Exp Hepatol       Date:  2020-10-06
  6 in total

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