Literature DB >> 27662508

Economic and care considerations of Marfan syndrome.

Carl Rudolf Blankart1, Ricarda Milstein1, Meike Rybczynski2, Helke Schüler2, Yskert von Kodolitsch2.   

Abstract

INTRODUCTION: Marfan syndrome is a rare multisystem disease of the connective tissue, which affects multiple organ systems. advances in healthcare have doubled the life-expectancy of patients over the past three decades. to date, there is no comprehensive review that consolidates economic considerations and care for marfan patients. Areas covered: Present research suggests that there may be a link between treatment pattern, disease progression and economic costs of Marfan syndrome. It indicates that an early detection of the disease and preventive interventions achieve a dual aim. From a patient perspective, it may reduce the amount of emergency surgery or intervention, and inpatient stays. In addition, it slows disease progression, lowers lifestyle restrictions, reduces psychological stress, and improves health-related quality of life. Expert commentary: Early detection and preventive measures are likely to achieve a dual aim by simultaneously containing costs and reducing the number and length of inpatient stays.

Entities:  

Keywords:  FBN1; Loeys-Dietz syndrome; Marfan syndrome; TGFBR2; costs; decision-making; economy; gene; healthcare; surgery

Mesh:

Year:  2016        PMID: 27662508     DOI: 10.1080/14737167.2016.1240619

Source DB:  PubMed          Journal:  Expert Rev Pharmacoecon Outcomes Res        ISSN: 1473-7167            Impact factor:   2.217


  5 in total

1.  Genetic diagnostics of inherited aortic diseases : Medical strategy analysis.

Authors:  Y von Kodolitsch; K Kutsche
Journal:  Herz       Date:  2017-08       Impact factor: 1.443

2.  What hinders congenital ectopia lentis patients' follow-up visits? A qualitative study.

Authors:  Jianqiang Lin; Ni Gong; Qianzhong Cao; Yijing Zhou; Yitingxue Cai; Guangming Jin; Charlotte Aimee Young; Jing Yang; Yiyao Wang; Danying Zheng
Journal:  BMJ Open       Date:  2020-03-12       Impact factor: 2.692

3.  Sleep apnea predicts cardiovascular death in patients with Marfan syndrome: a cohort study.

Authors:  Nele Gessler; Peter Wohlmuth; Omar Anwar; Eike Sebastian Debus; Christian Eickholt; Melanie A Gunawardene; Samer Hakmi; Kathrin Heitmann; Meike Rybczynski; Helke Schueler; Sara Sheikhzadeh; Eike Tigges; Gunther H Wiest; Stephan Willems; Ekaterina Adam; Yskert von Kodolitsch
Journal:  EPMA J       Date:  2022-07-29       Impact factor: 8.836

4.  Proof-of-Concept: Antisense Oligonucleotide Mediated Skipping of Fibrillin-1 Exon 52.

Authors:  Jessica M Cale; Kane Greer; Sue Fletcher; Steve D Wilton
Journal:  Int J Mol Sci       Date:  2021-03-27       Impact factor: 5.923

5.  Multidisciplinary aortopathy clinics: A systematic scoping review of the literature and evaluation of patient experiences from a newly started clinic in Norway.

Authors:  Trine Bathen; Kirsten Krohg-Sørensen; Ingeborg B Lidal
Journal:  Am J Med Genet A       Date:  2020-08-19       Impact factor: 2.578

  5 in total

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