Louis Jacob1, Ji Won Han2, Tae Hui Kim3, Joon Hyuk Park4, Seok Bum Lee5, Jung Jae Lee5, Seung-Ho Ryu6, Shin-Kyeom Kim7, Jong Chul Yoon8, Jin Hyeong Jhoo9, Jeong Lan Kim10, Kyung Phil Kwak11, Seok Woo Moon12, Bong Jo Kim13, Dong Young Lee14, Ki Woong Kim2,14,15. 1. Department of Biology, École Normale Supérieure de Lyon, Lyon, France. 2. Department of Neuropsychiatry, Seoul National University Bundang Hospital, Bundang-gu, Seongnam-si, Gyeonggi-do, Korea. 3. Department of Psychiatry, Yonsei University Wonju Severance Christian Hospital, Wonju-si, Gangwon-do, Korea. 4. Department of Neuropsychiatry, Jeju National University Hospital, Jeju Self-Governing Province, Korea. 5. Department of Psychiatry, Dankook University Hospital, Cheonan-si, Chungcheongnam-do, Korea. 6. Department of Psychiatry, School of Medicine, Konkuk University, Konkuk University Medical Center, Gwangjin-gu, Seoul, Korea. 7. Department of Neuropsychiatry, Soonchunhyang University Bucheon Hospital, Wonmi-gu, Bucheon-si, Gyeonggi-do, Korea. 8. Department of Neuropsychiatry, Kyunggi Provincial Hospital for the Elderly, Giheung-gu, Yongin-si, Gyeonggi-do, Korea. 9. Department of Neuropsychiatry, Kangwon National University Hospital, Chuncheon-si, Gangwon-do, Korea. 10. Department of Psychiatry, Chungnam National University Hospital, Jung-gu, Daejeon, Korea. 11. Department of Psychiatry, Dongguk Medical Center, Seokjang-dong, Gyeongju-si, Gyeongsangbuk-do, Korea. 12. Department of Psychiatry, Konkuk University Chungju Hospital, Chungju-si, Chungcheongbuk-do, Korea. 13. Department of Psychiatry, Gyeongsang National University, School of Medicine, Jinju-si, Gyeongnam-do, Korea. 14. Department of Psychiatry, Seoul National University, College of Medicine, Jongno-gu, Seoul, Korea. 15. Department of Brain and Cognitive Science, Seoul National University College of Natural Sciences, Gwanak-gu, Seoul, Korea.
Abstract
BACKGROUND: Measurements of patient quality of life (QoL) play a major role in the management of dementia. OBJECTIVE: We investigated the self-proxy discrepancy of QoL ratings in the elderly and the impact of dementia severity on the discrepancy. METHODS: QoL of 718 patients with dementia and 651 non-demented elderly were rated by themselves and their caregivers (CG) using the Quality of Life-Alzheimer's Disease (QoL-AD). The impact of the rater on the total and item scores of QoL-AD was analyzed using repeated measures ANOVA and differential response patterns between self and proxy were analyzed using differential item functioning (DIF) analysis. RESULTS: Self-rated scores were higher than CG-rated scores in all diagnostic groups. The interaction between rater and diagnostic group was significant in total QoL-AD score and 5 item scores ('memory', 'marriage', 'chores around the house', 'do things for fun', and 'life as a whole'). The strength of the DIF increased with advancing dementia in these items. CONCLUSION: Self-proxy rating discrepancy of QoL was influenced by the presence and severity of dementia only in five items.
BACKGROUND: Measurements of patient quality of life (QoL) play a major role in the management of dementia. OBJECTIVE: We investigated the self-proxy discrepancy of QoL ratings in the elderly and the impact of dementia severity on the discrepancy. METHODS: QoL of 718 patients with dementia and 651 non-demented elderly were rated by themselves and their caregivers (CG) using the Quality of Life-Alzheimer's Disease (QoL-AD). The impact of the rater on the total and item scores of QoL-AD was analyzed using repeated measures ANOVA and differential response patterns between self and proxy were analyzed using differential item functioning (DIF) analysis. RESULTS: Self-rated scores were higher than CG-rated scores in all diagnostic groups. The interaction between rater and diagnostic group was significant in total QoL-AD score and 5 item scores ('memory', 'marriage', 'chores around the house', 'do things for fun', and 'life as a whole'). The strength of the DIF increased with advancing dementia in these items. CONCLUSION: Self-proxy rating discrepancy of QoL was influenced by the presence and severity of dementia only in five items.
Entities:
Keywords:
Caregiver; dementia; discrepancy; proxy; quality of life; self