Literature DB >> 27661456

Pd-Catalyzed Carboamination of Alkylidenecyclopropanes: Synthesis of Congested Pyrrolidines and Piperidines.

Phillip R Lazzara1, Keegan P Fitzpatrick1, Chad C Eichman1.   

Abstract

The synthesis of densely functionalized N-heterocycles is an ongoing challenge in chemical synthesis. Herein, we report an efficient method for the construction of pyrrolidine and piperidine scaffolds using a palladium-catalyzed carboamination of alkylidenecyclopropanes.
© 2016 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim.

Entities:  

Keywords:  aminoarylation; carboamination; homogeneous catalysis; nitrogen heterocycles; palladium catalysis

Year:  2016        PMID： 27661456     DOI： 10.1002/chem.201604077

Source DB:  PubMed          Journal:  Chemistry        ISSN： 0947-6539            Impact factor:   5.236


  2 in total

1.  Recent Developments in Pd(0)-Catalyzed Alkene Carboheterofunctionalization Reactions.

Authors:  Zachary J Garlets; Derick R White; John P Wolfe
Journal:  Asian J Org Chem       Date:  2017-03-10       Impact factor: 3.319

2.  Aldolase-Catalyzed Asymmetric Synthesis of N-Heterocycles by Addition of Simple Aliphatic Nucleophiles to Aminoaldehydes.

Authors:  Raquel Roldán; Karel Hernández; Jesús Joglar; Jordi Bujons; Teodor Parella; Wolf-Dieter Fessner; Pere Clapés
Journal:  Adv Synth Catal       Date:  2019-02-15       Impact factor: 5.837
  2 in total

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