Literature DB >> 27661424

Heterotopic Ossification: A Review of Current Understanding, Treatment, and Future.

Dafydd S Edwards1, Kevin M Kuhn, Benjamin K Potter, Jonathan A Forsberg.   

Abstract

Heterotopic ossification is the formation of bone at extraskeletal sites. The incidence of heterotopic ossification in military amputees from recent operations in Iraq and Afghanistan has been demonstrated to be as high as 65%. Heterotopic ossification poses problems to wound healing, rehabilitation, and prosthetic fitting. This article details the current evidence regarding its etiology, prevention, management, and research strategies.

Entities:  

Year:  2016        PMID： 27661424     DOI： 10.1097/BOT.0000000000000666

Source DB:  PubMed          Journal:  J Orthop Trauma        ISSN： 0890-5339            Impact factor:   2.512


  12 in total

Review 1.  Is heterotopic ossification getting nervous?: The role of the peripheral nervous system in heterotopic ossification.

Authors:  Eleanor L Davis; Alan R Davis; Zbigniew Gugala; Elizabeth A Olmsted-Davis
Journal:  Bone       Date:  2017-07-15       Impact factor: 4.398

2.  Breath of relief: apparent pulmonary nodule due to heterotopic ossification.

Authors:  Eric Abston; Robert Novaco; Stephanie Hon; Jonathan Scalera; Katrina Steiling
Journal:  Clin Case Rep       Date:  2018-04-06

3.  Local injection of a hexametaphosphate formulation reduces heterotopic ossification in vivo.

Authors:  T E Robinson; N M Eisenstein; S C Cox; R J A Moakes; A M Thompson; Z Ahmed; E A B Hughes; L J Hill; S A Stapley; L M Grover
Journal:  Mater Today Bio       Date:  2020-06-02

Review 4.  Targeting heterotopic ossification by inhibiting activin receptor‑like kinase 2 function (Review).

Authors:  Fuli Shi; Jiayu Gao; Junrong Zou; Ying Ying; Hui Lin
Journal:  Mol Med Rep       Date:  2019-08-06       Impact factor: 2.952

5.  Surgical Management of Shoulder Heterotopic Ossification.

Authors:  Justin Hallock; Larry D Field
Journal:  Arthrosc Tech       Date:  2019-09-18

6.  Methods for the reliable induction of heterotopic ossification in the conditional Alk2Q207D mouse.

Authors:  Haichun Pan; Nicole Fleming; Charles C Hong; Yuji Mishina; Daniel S Perrien
Journal:  J Musculoskelet Neuronal Interact       Date:  2020-03-03       Impact factor: 2.041

7.  Three-year follow-up of changes of cortical bone thickness after implantation of Endo-Exo-Prosthesis (EEP) for transfemoral amputees.

Authors:  Marcus Örgel; Emmanouil Liodakis; Pratya Jaratjitwilai; Afif Harb; Nils Wirries; Mohamed Omar; Christian Krettek; Horst-Heinrich Aschoff
Journal:  J Orthop Surg Res       Date:  2020-05-04       Impact factor: 2.359

8.  Heterotopic ossification in mice overexpressing Bmp2 in Tie2+ lineages.

Authors:  Donal MacGrogan; Paula Gómez-Apiñániz; Belén Prados; Raquel Del Toro; Tania Papoutsi; Pura Muñoz-Cánoves; Simón Méndez-Ferrer; José Luis de la Pompa
Journal:  Cell Death Dis       Date:  2021-07-22       Impact factor: 8.469

9.  Inhibition of overactive TGF-β attenuates progression of heterotopic ossification in mice.

Authors:  Xiao Wang; Fengfeng Li; Liang Xie; Janet Crane; Gehua Zhen; Yuji Mishina; Ruoxian Deng; Bo Gao; Hao Chen; Shen Liu; Ping Yang; Manman Gao; Manli Tu; Yiguo Wang; Mei Wan; Cunyi Fan; Xu Cao
Journal:  Nat Commun       Date:  2018-02-07       Impact factor: 14.919

Review 10.  Mechanism of traumatic heterotopic ossification: In search of injury-induced osteogenic factors.

Authors:  Rocky S Tuan
Journal:  J Cell Mol Med       Date:  2020-08-27       Impact factor: 5.310
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