Vasopressin and oxytocin express excitatory effects on respiratory and respiration-related neurones in the nuclei of the tractus solitarius in the cat.

The effects of the iontophoretic application of vasopressin and oxytocin were examined on the activity of single neurones recorded in the region of the nuclei of the tractus solitarius (NTS) of the cat that were functionally classified as respiratory neurones or presumed reflex interneurones. The excitatory effects observed in half to two-thirds of these neurones tested (n = 37) suggest a role of these peptides in respiratory control and further support recent evidence that their involvement in autonomic control may include an action in NTS.