Literature DB >> 27656547

The Hormonal Fingerprints and BMI: Implications for Risk Factors in Dental Caries and Malocclusion.

Goguladinne Naga Deepthi Priyanka1, Madu Ghanashyam Prasad2, Ambati Naga Radhakrishna3, Juvva Ramakrishna1, Velagapudi Jyothi4.   

Abstract

INTRODUCTION: The hormonal fingerprint is the ratio between 2(nd) and 4(th) digit lengths. It was evidenced in the medical scenario that it can be used as an indirect marker in many diseases like Coronary Heart Disease (CHD) and metabolic syndromes. As far as dentistry is concerned very few studies in the literature have been done to evaluate the influence of hormonal fingerprint on oral health, thus provoking us to formulate new method for predicting dental caries and malocclusion and its association with Body Mass Index (BMI). AIM: The purpose of this retrospective study was to highlight the role of new biological marker-Hormonal fingerprints in the early detection of malocclusion, caries, the influence of BMI on malocclusion and caries. We also attempted to study the correlation of BMI with hormonal fingerprints.
MATERIALS AND METHODS: A total of 300 children were randomly selected from both sexes of age group 10-15 years. The hormonal fingerprint was made by measuring the length ratio of the index and ring finger with the help of digital Vernier caliper. Anthropometric measures (weight in kilograms and height in metres) for the calculation of BMI were recorded. Caries assessment was done using standard mouth mirrors and Community Periodontal Index probes. DMFT index was followed for assessment of caries according to the WHO assessment form, 1997. Occlusal characteristics of the children evaluated were molar relation, anterior and posterior cross bite, open bite, deep bite, lower anterior crowding. All the factors were recorded by two investigators.
RESULTS: The results of the study showed that majority of the children among study population were having 2D:4D <1. The rate of occurrence of malocclusion was increasing with increase in the value of 2D:4D ratio with a statistically significant p-value of <0.001. Higher BMI values were associated with normal occlusal conditions (p= 0.041) and lower 2D:4D ratio (p= 0.037). High caries experience was noticed in children with malocclusion (p= 0.027) which further influences the caries susceptibility. Pearson's correlation test, t-test and ANOVA were used in the study for statistical analysis using SPSS software.
CONCLUSION: This study confirms the impact of hormones on incidence of malocclusion, BMI which in turn influences the caries index and could be used as an early predictor.

Entities:  

Keywords:  2D:4D ratio; Biological marker; Caries risk susceptibility; Obesity; Occlusal status

Year:  2016        PMID: 27656547      PMCID: PMC5028577          DOI: 10.7860/JCDR/2016/18197.8223

Source DB:  PubMed          Journal:  J Clin Diagn Res        ISSN: 0973-709X


  9 in total

1.  Masculinized finger length patterns in human males and females with congenital adrenal hyperplasia.

Authors:  Windy M Brown; Melissa Hines; Briony A Fane; S Marc Breedlove
Journal:  Horm Behav       Date:  2002-12       Impact factor: 3.587

2.  Prevalence of malocclusion and orthodontic treatment need in schoolchildren - An epidemiological study.

Authors:  Prasanna Kumar; S M Londhe; Atul Kotwal; Rajat Mitra
Journal:  Med J Armed Forces India       Date:  2012-09-28

3.  Hormonal fingerprints: a key to early diagnosis of caries.

Authors:  Priya Verma; Amitha M Hegde; R Narayanacharyulu
Journal:  Indian J Dent Res       Date:  2013 Nov-Dec

4.  2nd to 4th digit ratios, fetal testosterone and estradiol.

Authors:  S Lutchmaya; S Baron-Cohen; P Raggatt; R Knickmeyer; J T Manning
Journal:  Early Hum Dev       Date:  2004-04       Impact factor: 2.079

5.  The ratio of 2nd to 4th digit length: a predictor of sperm numbers and concentrations of testosterone, luteinizing hormone and oestrogen.

Authors:  J T Manning; D Scutt; J Wilson; D I Lewis-Jones
Journal:  Hum Reprod       Date:  1998-11       Impact factor: 6.918

6.  Prenatal influences on sexual orientation: digit ratio (2D:4D) and number of older siblings.

Authors:  Katariina Kangassalo; Mari Pölkki; Markus J Rantala
Journal:  Evol Psychol       Date:  2011-10-10

7.  Exploring the relation between body mass index, diet, and dental caries among 6-12-year-old children.

Authors:  A Elangovan; J Mungara; E Joseph
Journal:  J Indian Soc Pedod Prev Dent       Date:  2012 Oct-Dec

8.  Prevalence of Dental Caries in relation to Body Mass Index, Daily Sugar Intake, and Oral Hygiene Status in 12-Year-Old School Children in Mathura City: A Pilot Study.

Authors:  Prahlad Gupta; Nidhi Gupta; Harkanwal Preet Singh
Journal:  Int J Pediatr       Date:  2014-02-12

Review 9.  Body mass index and dental caries in children and adolescents: a systematic review of literature published 2004 to 2011.

Authors:  Merrilyn Hooley; Helen Skouteris; Cecile Boganin; Julie Satur; Nicky Kilpatrick
Journal:  Syst Rev       Date:  2012-11-21
  9 in total
  2 in total

1.  Early Prediction of Dental Caries using Hormonal Fingerprint in 6-12 Years Old Children: A Cross-sectional Study.

Authors:  Fahanna Beegum; Nubesh Khan; Sageena George; Anandaraj S
Journal:  Int J Clin Pediatr Dent       Date:  2022 May-Jun

2.  Association of Hormonal Fingerprints and Dental Caries: A Pilot Study.

Authors:  Akansha Rajawat; Chandrakanth Majeti; Uday Kumar Podugu; Mamta Kaushik; X Nagamaheshwari; Neha Mehra
Journal:  J Conserv Dent       Date:  2021-01-16
  2 in total

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