Literature DB >> 27655873

Use of aspirin as sole oral antiplatelet therapy in acute flow diversion for ruptured dissecting aneurysms.

Albert Ho Yuen Chiu1, Rajalakshmi Ramesh2, Jason Wenderoth1, Mark Davies3, Andrew Cheung4.   

Abstract

Subarachnoid hemorrhage secondary to rupture of a circumferential dissecting aneurysm continues to be a treatment dilemma. Vessel sacrifice, when possible, continues to be the safest option but in certain cases this is not possible due to lack of collateral supply. In such cases, coil assisted endovascular flow diversion has become a potential option but the requirement for dual antiplatelet therapy in an unsecured intracranial aneurysm continues to raise concern.We present a 48-year-old man with a World Federation of Neurological Surgeons grade 5 subarachnoid hemorrhage, secondary to a ruptured intradural left vertebral artery dissecting aneurysm, who was treated successfully with a pipeline embolization device with Shield technology using aspirin and a single intravenous loading dose of abciximab. To our knowledge, this is the first case of an acute flow diversion performed using only aspirin as the sole oral antiplatelet agent. 2016 BMJ Publishing Group Ltd.

Entities:  

Keywords:  Aneurysm; Flow Diverter; Hemorrhage; Platelets

Year:  2016        PMID: 27655873      PMCID: PMC5051367          DOI: 10.1136/bcr-2016-012657

Source DB:  PubMed          Journal:  BMJ Case Rep        ISSN: 1757-790X


  4 in total

1.  In-vitro thrombogenicity assessment of flow diversion and aneurysm bridging devices.

Authors:  Gaurav Girdhar; Junwei Li; Larisa Kostousov; John Wainwright; Wayne L Chandler
Journal:  J Thromb Thrombolysis       Date:  2015-11       Impact factor: 2.300

2.  Risk of ventriculostomy-related hemorrhage in patients with acutely ruptured aneurysms treated using stent-assisted coiling.

Authors:  David K Kung; Bruno A Policeni; Ana W Capuano; James D Rossen; Pascal M Jabbour; James C Torner; Matthew A Howard; David Hasan
Journal:  J Neurosurg       Date:  2010-10-15       Impact factor: 5.115

3.  Treatment of blister-like aneurysms with the pipeline embolization device.

Authors:  Nohra Chalouhi; Mario Zanaty; Stavropoula Tjoumakaris; L Fernando Gonzalez; David Hasan; David Kung; Robert H Rosenwasser; Pascal Jabbour
Journal:  Neurosurgery       Date:  2014-05       Impact factor: 4.654

4.  Pharmacodynamics of chimeric glycoprotein IIb/IIIa integrin antiplatelet antibody Fab 7E3 in high-risk coronary angioplasty.

Authors:  J E Tcheng; S G Ellis; B S George; D J Kereiakes; N S Kleiman; J D Talley; A L Wang; H F Weisman; R M Califf; E J Topol
Journal:  Circulation       Date:  1994-10       Impact factor: 29.690

  4 in total

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