OBJECTIVE: To investigate the influencing factors for asthma control level in children and the practicability of evaluation indicators for asthma. METHODS: A total of 185 children with asthma were enrolled. Questionnaires and pulmonary function test were used to evaluate the asthma control level and the factors influencing the control level. The correlation between evaluation indicators and asthma control level was analyzed. RESULTS: Among the 185 children with asthma, 139 (75.1%) achieved full control, 36 (19.5%) achieved partial control, and 10 (5.4%) had uncontrolled asthma. Application of inhaled corticosteroids and eosinophil count showed significant effects on asthma control level (P<0.05). There were significant differences in the percentage of forced expiratory volume in 1 second (FEV1%), fractional exhaled nitric oxide (FeNO), childhood asthma control test (C-ACT) questionnaire score, and pediatric asthma quality of life questionnaire (PAQLQ) score between the full control, partial control, and uncontrolled groups (P<0.05). In the children with asthma, FEV1% was positively correlated with C-ACT and PAQLQ scores (P<0.05), while there was no significant correlation between FEV1% and FeNO (P=0.214). CONCLUSIONS: Application of inhaled corticosteroids and eosinophil count are factors influencing asthma control in children. A combination of FEV1%, FeNO, C-ACT score, and PAQLQ score helps with the evaluation of asthma control level.
OBJECTIVE: To investigate the influencing factors for asthma control level in children and the practicability of evaluation indicators for asthma. METHODS: A total of 185 children with asthma were enrolled. Questionnaires and pulmonary function test were used to evaluate the asthma control level and the factors influencing the control level. The correlation between evaluation indicators and asthma control level was analyzed. RESULTS: Among the 185 children with asthma, 139 (75.1%) achieved full control, 36 (19.5%) achieved partial control, and 10 (5.4%) had uncontrolled asthma. Application of inhaled corticosteroids and eosinophil count showed significant effects on asthma control level (P<0.05). There were significant differences in the percentage of forced expiratory volume in 1 second (FEV1%), fractional exhaled nitric oxide (FeNO), childhood asthma control test (C-ACT) questionnaire score, and pediatric asthma quality of life questionnaire (PAQLQ) score between the full control, partial control, and uncontrolled groups (P<0.05). In the children with asthma, FEV1% was positively correlated with C-ACT and PAQLQ scores (P<0.05), while there was no significant correlation between FEV1% and FeNO (P=0.214). CONCLUSIONS: Application of inhaled corticosteroids and eosinophil count are factors influencing asthma control in children. A combination of FEV1%, FeNO, C-ACT score, and PAQLQ score helps with the evaluation of asthma control level.
Authors: C G Tischer; C Hohmann; E Thiering; O Herbarth; A Müller; J Henderson; R Granell; M P Fantini; L Luciano; A Bergström; I Kull; E Link; A von Berg; C E Kuehni; M-P F Strippoli; U Gehring; A Wijga; E Eller; C Bindslev-Jensen; T Keil; J Heinrich Journal: Allergy Date: 2011-09-19 Impact factor: 13.146
Authors: Hilary Pinnock; Monica Fletcher; Steve Holmes; Duncan Keeley; Jane Leyshon; David Price; Richard Russell; Jenny Versnel; Bronwen Wagstaff Journal: Prim Care Respir J Date: 2010-03
Authors: Erik-Jonas van de Griendt; Marieke Verkleij; J Menno Douwes; Wim M C van Aalderen; Rinie Geenen Journal: J Asthma Date: 2014-01-09 Impact factor: 2.515