Literature DB >> 27653602

The Tumor Microenvironment Represses T Cell Mitochondrial Biogenesis to Drive Intratumoral T Cell Metabolic Insufficiency and Dysfunction.

Nicole E Scharping, Ashley V Menk, Rebecca S Moreci, Ryan D Whetstone, Rebekah E Dadey, Simon C Watkins, Robert L Ferris, Greg M Delgoffe.   

Abstract

Entities:  

Year:  2016        PMID: 27653602     DOI: 10.1016/j.immuni.2016.08.009

Source DB:  PubMed          Journal:  Immunity        ISSN: 1074-7613            Impact factor:   31.745


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  68 in total

1.  Alteration of Tumor Metabolism by CD4+ T Cells Leads to TNF-α-Dependent Intensification of Oxidative Stress and Tumor Cell Death.

Authors:  Tsadik Habtetsion; Zhi-Chun Ding; Wenhu Pi; Tao Li; Chunwan Lu; Tingting Chen; Caixia Xi; Helena Spartz; Kebin Liu; Zhonglin Hao; Nahid Mivechi; Yuqing Huo; Bruce R Blazar; David H Munn; Gang Zhou
Journal:  Cell Metab       Date:  2018-06-07       Impact factor: 27.287

Review 2.  Regulation of T cell immunity by cellular metabolism.

Authors:  Zhilin Hu; Qiang Zou; Bing Su
Journal:  Front Med       Date:  2018-08-16       Impact factor: 4.592

3.  Clonal expansion of vaccine-elicited T cells is independent of aerobic glycolysis.

Authors:  Jared Klarquist; Alisha Chitrakar; Nathan D Pennock; Augustus M Kilgore; Trevor Blain; Connie Zheng; Thomas Danhorn; Kendra Walton; Li Jiang; Jie Sun; Christopher A Hunter; Angelo D'Alessandro; Ross M Kedl
Journal:  Sci Immunol       Date:  2018-09-07

4.  Kidney-infiltrating T cells in murine lupus nephritis are metabolically and functionally exhausted.

Authors:  Jeremy S Tilstra; Lyndsay Avery; Ashley V Menk; Rachael A Gordon; Shuchi Smita; Lawrence P Kane; Maria Chikina; Greg M Delgoffe; Mark J Shlomchik
Journal:  J Clin Invest       Date:  2018-09-24       Impact factor: 14.808

Review 5.  Oxidative Stress in Cancer.

Authors:  John D Hayes; Albena T Dinkova-Kostova; Kenneth D Tew
Journal:  Cancer Cell       Date:  2020-07-09       Impact factor: 31.743

6.  Oncolytic Viruses Engineered to Enforce Leptin Expression Reprogram Tumor-Infiltrating T Cell Metabolism and Promote Tumor Clearance.

Authors:  Dayana B Rivadeneira; Kristin DePeaux; Yiyang Wang; Aditi Kulkarni; Tracy Tabib; Ashley V Menk; Padmavathi Sampath; Robert Lafyatis; Robert L Ferris; Saumendra N Sarkar; Stephen H Thorne; Greg M Delgoffe
Journal:  Immunity       Date:  2019-08-27       Impact factor: 31.745

7.  Predictors of response and resistance to checkpoint inhibitors in solid tumors.

Authors:  Sanjana V Rao; Amy E Moran; Julie N Graff
Journal:  Ann Transl Med       Date:  2017-12

Review 8.  Manipulating the tumor microenvironment by adoptive cell transfer of CAR T-cells.

Authors:  Kavitha Gowrishankar; Lucy Birtwistle; Kenneth Micklethwaite
Journal:  Mamm Genome       Date:  2018-07-09       Impact factor: 2.957

Review 9.  Targeting mitochondria in cancer: current concepts and immunotherapy approaches.

Authors:  Sergey Pustylnikov; Francesca Costabile; Silvia Beghi; Andrea Facciabene
Journal:  Transl Res       Date:  2018-07-31       Impact factor: 7.012

10.  Epigenetic Control of Cdkn2a.Arf Protects Tumor-Infiltrating Lymphocytes from Metabolic Exhaustion.

Authors:  Brian Koss; Bradley D Shields; Erin M Taylor; Aaron J Storey; Stephanie D Byrum; Allen J Gies; Charity L Washam; Samrat Roy Choudhury; Jeong Hyun Ahn; Hidetaka Uryu; Jason B Williams; Kimberly J Krager; Tung-Chin Chiang; Samuel G Mackintosh; Rick D Edmondson; Nukhet Aykin-Burns; Thomas F Gajewski; Gang Greg Wang; Alan J Tackett
Journal:  Cancer Res       Date:  2020-10-01       Impact factor: 12.701

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