Literature DB >> 27652326

Vesicular trafficking regulators are new players in breast cancer progression: Role of TOM1L1 in ERBB2-dependent invasion.

Clément Chevalier1, Serge Roche1, Christine Bénistant2.   

Abstract

ERBB2 (v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 2) amplification is associated with invasive breast cancer. We discovered that TOM1L1 (target of myb1-like 1) and ERBB2 co-amplification defines a novel mechanism involved in breast cancer metastatic progression. Upregulation of the vesicular trafficking protein TOM1L1 enhances plasma membrane delivery of membrane-type 1 matrix metalloprotease (MT1-MMP) for efficient extracellular matrix degradation and tumor cell dissemination.

Entities:  

Keywords:  Breast cancer; metastasis; tumor cell signaling; tyrosine kinase; vesicular trafficking

Year:  2016        PMID： 27652326      PMCID： PMC4972109          DOI： 10.1080/23723556.2016.1182241

Source DB:  PubMed          Journal:  Mol Cell Oncol        ISSN： 2372-3556


  9 in total

1.  Genomic and expression profiling of chromosome 17 in breast cancer reveals complex patterns of alterations and novel candidate genes.

Authors:  Béatrice Orsetti; Mélanie Nugoli; Nathalie Cervera; Laurence Lasorsa; Paul Chuchana; Lisa Ursule; Catherine Nguyen; Richard Redon; Stanislas du Manoir; Carmen Rodriguez; Charles Theillet
Journal:  Cancer Res       Date:  2004-09-15       Impact factor: 12.701

2.  The adaptor protein Tom1L1 is a negative regulator of Src mitogenic signaling induced by growth factors.

Authors:  Mélanie Franco; Olivia Furstoss; Valérie Simon; Chrsitine Benistant; Wan Jing Hong; Serge Roche
Journal:  Mol Cell Biol       Date:  2006-03       Impact factor: 4.272

Review 3.  Molecular mechanisms underlying ErbB2/HER2 action in breast cancer.

Authors:  D Harari; Y Yarden
Journal:  Oncogene       Date:  2000-12-11       Impact factor: 9.867

4.  'Srcasm: a novel Src activating and signaling molecule.

Authors:  John T Seykora; Lijuan Mei; G Paolo Dotto; Paul L Stein
Journal:  J Biol Chem       Date:  2001-11-15       Impact factor: 5.157

5.  GGA3 functions as a switch to promote Met receptor recycling, essential for sustained ERK and cell migration.

Authors:  Christine Anna Parachoniak; Yi Luo; Jasmine Vanessa Abella; James H Keen; Morag Park
Journal:  Dev Cell       Date:  2011-06-14       Impact factor: 12.270

Review 6.  The emerging role of VHS domain-containing Tom1, Tom1L1 and Tom1L2 in membrane trafficking.

Authors:  Tuanlao Wang; Ning Sheng Liu; Li-Fong Seet; Wanjin Hong
Journal:  Traffic       Date:  2010-07-01       Impact factor: 6.215

Review 7.  Matrix invasion by tumour cells: a focus on MT1-MMP trafficking to invadopodia.

Authors:  Renaud Poincloux; Floria Lizárraga; Philippe Chavrier
Journal:  J Cell Sci       Date:  2009-09-01       Impact factor: 5.285

8.  A RAB5/RAB4 recycling circuitry induces a proteolytic invasive program and promotes tumor dissemination.

Authors:  Emanuela Frittoli; Andrea Palamidessi; Paola Marighetti; Stefano Confalonieri; Fabrizio Bianchi; Chiara Malinverno; Giovanni Mazzarol; Giuseppe Viale; Ines Martin-Padura; Massimilliano Garré; Dario Parazzoli; Valentina Mattei; Salvatore Cortellino; Giovanni Bertalot; Pier Paolo Di Fiore; Giorgio Scita
Journal:  J Cell Biol       Date:  2014-07-21       Impact factor: 10.539

9.  TOM1L1 drives membrane delivery of MT1-MMP to promote ERBB2-induced breast cancer cell invasion.

Authors:  Clément Chevalier; Guillaume Collin; Simon Descamps; Heiani Touaitahuata; Valérie Simon; Nicolas Reymond; Laurent Fernandez; Pierre-Emmanuel Milhiet; Virginie Georget; Serge Urbach; Laurence Lasorsa; Béatrice Orsetti; Florence Boissière-Michot; Evelyne Lopez-Crapez; Charles Theillet; Serge Roche; Christine Benistant
Journal:  Nat Commun       Date:  2016-02-22       Impact factor: 14.919
  9 in total
  3 in total

Review 1.  Vesicular trafficking-related proteins as the potential therapeutic target for breast cancer.

Authors:  Mohd Mughees; Himanshu Chugh; Saima Wajid
Journal:  Protoplasma       Date:  2019-12-11       Impact factor: 3.356

2.  Regulation of MT1-MMP Activity through Its Association with ERMs.

Authors:  Henar Suárez; Soraya López-Martín; Victor Toribio; Moreno Zamai; María Victoria Hernández-Riquer; Laura Genís; Alicia García Arroyo; María Yáñez-Mó
Journal:  Cells       Date:  2020-02-03       Impact factor: 6.600

3.  Integrative genomic analysis of N6-methyladenosine-single nucleotide polymorphisms (m6A-SNPs) associated with breast cancer.

Authors:  Zixue Xuan; Yiwen Zhang; Jinying Jiang; Xiaowei Zheng; Xiaoping Hu; Xiuli Yang; Yanfei Shao; Guobing Zhang; Ping Huang
Journal:  Bioengineered       Date:  2021-12       Impact factor: 3.269
  3 in total

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