Literature DB >> 27651699

Cervical Cord Compression as Initial Presentation of Papillary Thyroid Carcinoma: a Case Report.

Veda Padma Priya Selvakumar1, Ashish Goel1, Kapil Kumar1.   

Abstract

Cervical cord compression secondary to extension of a long standing papillary thyroid carcinoma as well as multiple cases of distal cord compression from occult follicular thyroid carcinoma have been reported. But cervical cord compression from Papillary Thyroid Carcinoma has not been reported so far. Forty eight year old lady presented with progressive quadriparesis of 2 months duration. MRI of the cervical spine showed destructive lesion with soft tissue component in vertebral bodies and posterior elements of C4-C6 vertebrae with cord compression along with a large thyroid mass extending to retrosternal region likely malignant. USG guided FNAC & Biopsy of thyroid lesion was inconclusive. She underwent Preoperative Selective angioembolisation for vertebral metastasis followed by total thyroidectomy with cervical cord decompression, bone grafting and plating. HPE reported follicular variant of Papillary Thyroid carcinoma. Four weeks postoperatively she underwent radioiodine ablation by 263 mci of I 131. She then received palliative EBRT to cervical and dorsal spine 30 Gy/10 fractions. She is alive and neurologically stable at 6 months follow up. Papillary thyroid carcinoma has an excellent prognosis. Hence a prompt management of primary disease and aggressive approach to metastatic lesion may prolong survival and allow favorable prognosis.

Entities:  

Keywords:  Malignant spinal cord compression; Metastatic ca thyroid; Spinal metastases; Vertebral metastases

Year:  2015        PMID: 27651699      PMCID: PMC5016321          DOI: 10.1007/s13193-015-0460-6

Source DB:  PubMed          Journal:  Indian J Surg Oncol        ISSN: 0975-7651


  5 in total

1.  Metastatic disease of the spine.

Authors:  K D Harrington
Journal:  J Bone Joint Surg Am       Date:  1986-09       Impact factor: 5.284

Review 2.  Metastatic epidural spinal cord compression: update on management.

Authors:  Thomas N Byrne; Lawrence F Borges; Jay S Loeffler
Journal:  Semin Oncol       Date:  2006-06       Impact factor: 4.929

3.  The role of operations for distantly metastatic well-differentiated thyroid carcinoma.

Authors:  Alexander Stojadinovic; Margo Shoup; Ronald A Ghossein; Aviram Nissan; Murray F Brennan; Jatin P Shah; Ashok R Shaha
Journal:  Surgery       Date:  2002-06       Impact factor: 3.982

Review 4.  Follicular variant of papillary thyroid carcinoma: a diagnostic challenge for clinicians and pathologists.

Authors:  A Salajegheh; E B Petcu; R A Smith; A K-Y Lam
Journal:  Postgrad Med J       Date:  2008-02       Impact factor: 2.401

Review 5.  Spinal metastasis in thyroid cancer.

Authors:  Sami Ramadan; Mohamed A Ugas; Richard J Berwick; Manisha Notay; Hyongyu Cho; Waseem Jerjes; Peter V Giannoudis
Journal:  Head Neck Oncol       Date:  2012-06-25
  5 in total
  2 in total

1.  Thoracic Spinal Cord Compression Secondary to Metastatic Papillary Thyroid Carcinoma: An Unusual Oncological Phenomenon.

Authors:  Eltaib A Saad; Monzer Abdalla; Abdalaziz M Awadelkarim; Osama Elkhider; Mohamed Agab; Akram Babkir; Isra Idris; Dorota Filipiuk
Journal:  Cureus       Date:  2022-04-17

2.  An upper cervical cord compression secondary to occult follicular thyroid carcinoma metastases successfully treated with multiple radioiodine therapies: A clinical case report.

Authors:  Ping Dong; Ni Chen; Lin Li; Rui Huang
Journal:  Medicine (Baltimore)       Date:  2017-10       Impact factor: 1.817

  2 in total

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