Literature DB >> 27651552

Treatment of iron deficiency anaemia with the natural hematinic Carbaodeim.

Mugahid Faroug Mohamed Ali1, Mohammed Osman Swar2, Atika Mohamed Osman2.   

Abstract

Iron deficiency anaemia is frequently seen in the paediatric age group. Modifying the treatment options according to the affected area resources will help accessibility and compliance to treatment. Response of children with Iron deficiency anaemia to a natural hematinic (Carboadeim) versus iron syrup plus folic acid treatment was compared in this study. This is a prospective, interventional, controlled, hospital-based study conducted among children with iron deficiency anaemia residing in Hussein Village, Gezira State who attended Giad Hospital. Patients were randomly divided into two groups; the control received iron supplements and folic acid, and the case received a combination of carrots, baobab (Adansonia digitata) and godeim (Grewia tenax) which is known as (Carboadeim). Blood tests were taken for investigations at start of treatment, after 7-10 days, 6 weeks and 3 months. Complete blood count, reticulocyte count and serum ferritin were taken as indicators. The mean haemoglobin level initially in the cases and controls was 7.38 and 7.35 gm/dL, respectively; after three months the mean was 11.67 and 11.384 gm/dL, respectively. The mean serum ferritin in the case and control groups was found to be 10.30 and 10.87 ng/ml, respectively at the start of treatment; and after 3 months they were reported to be 44.34 and 75.7 ng/ml confirming the positive response to treatment by Carboadeim. In conclusion Carboadeim is a naturally available and cost-effective hematinic blend that might be added to the food menu as a supplement as well as a treatment of nutritional anaemia in children.

Entities:  

Keywords:  Carbaodeim; Iron deficiency anaemia; Natural hematinic

Year:  2016        PMID: 27651552      PMCID: PMC5025931     

Source DB:  PubMed          Journal:  Sudan J Paediatr        ISSN: 0256-4408


  11 in total

Review 1.  Forging a field: the golden age of iron biology.

Authors:  Nancy C Andrews
Journal:  Blood       Date:  2008-07-15       Impact factor: 22.113

2.  Reticulocyte parameters: markers of early response to oral treatment in children with severe iron-deficiency anemia.

Authors:  Emilia Parodi; Maria Teresa Giraudo; Mirella Davitto; Giulia Ansaldi; Anna Mondino; Letizia Garbarini; Annamartina Franzil; Raffaela Mazzone; Giovanna Russo; Ugo Ramenghi
Journal:  J Pediatr Hematol Oncol       Date:  2012-08       Impact factor: 1.289

3.  Carbaodeim: A natural haematinic blend for treatment of dimorphic anemia of malnutrition.

Authors:  Mohamed Osman Swar; Atika Mohamed Osman
Journal:  Sudan J Paediatr       Date:  2014

Review 4.  Evaluation of anemia in children.

Authors:  Jennifer Janus; Sarah K Moerschel
Journal:  Am Fam Physician       Date:  2010-06-15       Impact factor: 3.292

5.  Iron deficiency anemia among children: Addressing a global public health problem within a Canadian context.

Authors:  Anna Christofides; Claudia Schauer; Stanley H Zlotkin
Journal:  Paediatr Child Health       Date:  2005-12       Impact factor: 2.253

6.  Modulation of hepcidin production during hypoxia-induced erythropoiesis in humans in vivo: data from the HIGHCARE project.

Authors:  Alberto Piperno; Stefania Galimberti; Raffaella Mariani; Sara Pelucchi; Giulia Ravasi; Carolina Lombardi; Grzegorz Bilo; Miriam Revera; Andrea Giuliano; Andrea Faini; Veronica Mainini; Mark Westerman; Tomas Ganz; Maria Grazia Valsecchi; Giuseppe Mancia; Gianfranco Parati
Journal:  Blood       Date:  2010-12-13       Impact factor: 22.113

7.  Clinical utility of the reticulocyte hemoglobin content in the diagnosis of iron deficiency.

Authors:  Alan E Mast; Morey A Blinder; Qing Lu; Sherri Flax; Dennis J Dietzen
Journal:  Blood       Date:  2002-02-15       Impact factor: 22.113

8.  Localization of iron metabolism-related mRNAs in rat liver indicate that HFE is expressed predominantly in hepatocytes.

Authors:  An-Sheng Zhang; Shigang Xiong; Hidekazu Tsukamoto; Caroline A Enns
Journal:  Blood       Date:  2003-10-16       Impact factor: 22.113

9.  Hepcidin, a key regulator of iron metabolism, is transcriptionally activated by p53.

Authors:  Orly Weizer-Stern; Konstantin Adamsky; Ofer Margalit; Osnat Ashur-Fabian; David Givol; Ninette Amariglio; Gideon Rechavi
Journal:  Br J Haematol       Date:  2007-07       Impact factor: 6.998

Review 10.  Iron deficiency anemia.

Authors:  Dinaz Z Naigamwalla; Jinelle A Webb; Urs Giger
Journal:  Can Vet J       Date:  2012-03       Impact factor: 1.008

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