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Literature DB >> 27651406

Polycythaemia: an unusual presentation of multiple myeloma.

Elaine J Hutchison¹, Josephine A Taverna², Qi Yu¹, Andrew M Yeager².

Abstract

In contrast to anaemia, polycythaemia is a distinctly uncommon finding in patients with multiple myeloma. We describe the presence of otherwise unexplained polycythaemia in a 57-year-old Caucasian man who was found to have IgG κ multiple myeloma. After treatment of myeloma, the polycythaemia resolved. We reviewed previous reports of polycythaemia associated with multiple myeloma and discuss potential pathophysiological mechanisms that link these 2 conditions. 2016 BMJ Publishing Group Ltd.

Entities: Disease Species

Mesh：

Substances：

Year: 2016 PMID： 27651406 PMCID： PMC5030570 DOI： 10.1136/bcr-2016-216686

Source DB: PubMed Journal: BMJ Case Rep ISSN： 1757-790X

29 in total

1. Case records of the Massachusetts General Hospital. Case 23-2010. A 49-year-old man with erythrocytosis, perinephric fluid collections, and renal failure.

Authors: Hasan Bazari; Eyal C Attar; Douglas M Dahl; Raul N Uppot; Robert B Colvin
Journal: N Engl J Med Date: 2010-07-29 Impact factor: 91.245

2. Long-term complete clinical and hematological responses of the TEMPI syndrome after autologous stem cell transplantation.

Authors: S S Kenderian; F G Rosado; D B Sykes; J D Hoyer; M Q Lacy
Journal: Leukemia Date: 2015-10-26 Impact factor: 11.528

Review 3. Hematological paraneoplastic syndromes.

Authors: H Staszewski
Journal: Semin Oncol Date: 1997-06 Impact factor: 4.929

4. Multiple myeloma associated with polycythemia; report of four cases.

Authors: J H LAWRENCE; R L ROSENTHAL
Journal: Am J Med Sci Date: 1949-08 Impact factor: 2.378

5. The TEMPI syndrome--a novel multisystem disease.

Authors: David B Sykes; Wilfried Schroyens; Casey O'Connell
Journal: N Engl J Med Date: 2011-08-04 Impact factor: 91.245

Review 6. JAK2 mutation-negative secondary erythrocytosis in smoldering plasma cell myeloma: a case study and review of the literature.

Authors: Sang-Guk Lee; Gayoung Lim; Sun Young Cho; Jin-Tae Suh; Hee Joo Lee; Sun Kyung Baek; Woo-In Lee; Hwi-Joong Yoon; Tae Sung Park
Journal: Acta Haematol Date: 2011-07-27 Impact factor: 2.195

Polycythaemia: an unusual presentation of multiple myeloma.

1. Case records of the Massachusetts General Hospital. Case 23-2010. A 49-year-old man with erythrocytosis, perinephric fluid collections, and renal failure.

2. Long-term complete clinical and hematological responses of the TEMPI syndrome after autologous stem cell transplantation.

Review 3. Hematological paraneoplastic syndromes.

4. Multiple myeloma associated with polycythemia; report of four cases.

5. The TEMPI syndrome--a novel multisystem disease.

Review 6. JAK2 mutation-negative secondary erythrocytosis in smoldering plasma cell myeloma: a case study and review of the literature.

7. Concurrence of multiple myeloma and idiopathic erythrocytosis.

8. Erythropoiesis in multiple myeloma: defective red cell production due to inappropriate erythropoietin production.

9. Polycythemia associated with myeloma.

10. Bortezomib to treat the TEMPI syndrome.

Review 1. TEMPI Syndrome: Update on Clinical Features, Management, and Pathogenesis.

2. Concurrent Polycythemia of Undetermined Etiology and Smouldering Plasma Cell Myeloma.