Literature DB >> 27650937

Repeat Robotic Partial Nephrectomy: Characteristics, Complications, and Renal Functional Outcomes.

Matthew J Watson1, Abhinav Sidana1, Annerleim Walton Diaz1, M Minhaj Siddiqui2, Ryan A Hankins3, Gennady Bratslavsky4, W Marston Linehan1, Adam R Metwalli1.   

Abstract

INTRODUCTION: Multifocal and hereditary kidney cancers often require repeated ipsilateral nephron sparing procedures with higher blood loss and complication rates compared to first time renal surgery. Consequently, many surgeons avoid minimally invasive techniques in the setting. We present the characteristics, complications, and short-term renal functional outcomes of patients who underwent a repeat robotic partial nephrectomy (rRPNx).
MATERIALS AND METHODS: A database was retrospectively reviewed to identify patients who underwent robotic partial nephrectomies between January 2007 and December 2013. Selection criteria for the rRPNx cohort included patients who had undergone at least two ipsilateral renal surgeries, with the second procedure being an rRPNx. All other patients comprised the initial robotic partial nephrectomy (iRPNx) group.
RESULTS: One hundred twenty-four patients who underwent robotic partial nephrectomy during the study period were identified. rRPNx constituted 26 (21%) of the total cases. Age of the rRPNx cohort was similar (p = 0.56), but number of tumors resected was two-fold greater in the rRPNx group (p = 0.44). Neither surgery time nor renal clamp time was significantly longer in either group (p = 0.18 and p = 0.65, respectively). Importantly, estimated blood loss (EBL) was significantly larger than in the iRPNx group (p = 0.01). Both groups had similar intravenous pain medication administration durations (p = 0.32), but postsurgical length of stay was greater for the rRPNx patients (p = 0.011). There were no significant differences in clavian complication rates (p = 0.17-0.39), with the exception of urine leak which occurred more frequently in the rRPNx group (p = 0.01). There was no difference in percent change in serum creatinine or estimated glomerular filtration rate (p = 0.89 and p = 0.67, respectively).
CONCLUSIONS: rRPNx is safe and feasible in select patients. EBL, postoperative lengths of stay, and urine leak were the only factors significantly associated with rRPNx compared to iRPNx. Patient 3-month follow-up revealed excellent and comparable outcomes between the two groups.

Entities:  

Keywords:  laparoscopy approach; renal cancer; robotics

Mesh:

Substances:

Year:  2016        PMID: 27650937      PMCID: PMC5107716          DOI: 10.1089/end.2016.0517

Source DB:  PubMed          Journal:  J Endourol        ISSN: 0892-7790            Impact factor:   2.942


  24 in total

Review 1.  Nephron sparing surgery for renal tumors: indications, techniques and outcomes.

Authors:  R G Uzzo; A C Novick
Journal:  J Urol       Date:  2001-07       Impact factor: 7.450

Review 2.  Comparison of perioperative outcomes between robotic and laparoscopic partial nephrectomy: a systematic review and meta-analysis.

Authors:  Ji Eun Choi; Ji Hye You; Dae Keun Kim; Koon Ho Rha; Seon Heui Lee
Journal:  Eur Urol       Date:  2015-01-06       Impact factor: 20.096

3.  Outcome of stage T2 or greater renal cell cancer treated with partial nephrectomy.

Authors:  Rodney H Breau; Paul L Crispen; Rafael E Jimenez; Christine M Lohse; Michael L Blute; Bradley C Leibovich
Journal:  J Urol       Date:  2010-01-18       Impact factor: 7.450

4.  Postoperative elevation in creatine kinase and its impact on renal function in patients undergoing complex partial nephrectomy.

Authors:  Abhinav Sidana; Annerleim Walton-Diaz; Hong Truong; M Minhaj Siddiqui; Ning Miao; Johanna Shih; Andrew Mannes; Gennady Bratslavsky; W Marston Linehan; Adam R Metwalli
Journal:  Int Urol Nephrol       Date:  2016-04-19       Impact factor: 2.370

Review 5.  The genetic basis of cancer of the kidney.

Authors:  W Marston Linehan; McClellan M Walther; Berton Zbar
Journal:  J Urol       Date:  2003-12       Impact factor: 7.450

6.  Partial nephrectomy after previous radio frequency ablation: the National Cancer Institute experience.

Authors:  Keith J Kowalczyk; H Brooks Hooper; W Marston Linehan; Peter A Pinto; Bradford J Wood; Gennady Bratslavsky
Journal:  J Urol       Date:  2009-09-16       Impact factor: 7.450

7.  Risk factors and management of urine leaks after partial nephrectomy.

Authors:  Joshua J Meeks; Lee C Zhao; Neema Navai; Kent T Perry; Robert B Nadler; Norm D Smith
Journal:  J Urol       Date:  2008-10-18       Impact factor: 7.450

8.  Initial experience with robot assisted partial nephrectomy for multiple renal masses.

Authors:  Ronald Boris; Miguel Proano; W Marston Linehan; Peter A Pinto; Gennady Bratslavsky
Journal:  J Urol       Date:  2009-08-14       Impact factor: 7.450

9.  A new equation to estimate glomerular filtration rate.

Authors:  Andrew S Levey; Lesley A Stevens; Christopher H Schmid; Yaping Lucy Zhang; Alejandro F Castro; Harold I Feldman; John W Kusek; Paul Eggers; Frederick Van Lente; Tom Greene; Josef Coresh
Journal:  Ann Intern Med       Date:  2009-05-05       Impact factor: 25.391

10.  Renal functional outcomes after robotic multiplex partial nephrectomy: the National Cancer Institute experience with robotic partial nephrectomy for 3 or more tumors in a single kidney.

Authors:  Ryan A Hankins; Annerleim Walton-Diaz; Hong Truong; Joanna Shih; Gennady Bratslavsky; Peter A Pinto; W Marston Linehan; Adam R Metwalli
Journal:  Int Urol Nephrol       Date:  2016-08-11       Impact factor: 2.370

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  4 in total

1.  Re: Multiple Tumor Excisions in Ipsilateral Kidney Increase Complications After Partial Nephrectomy (From: Maurice MJ, Ramirez D, Nelson R, et al. J Endourology 2016;30:1200-1206).

Authors:  Adam R Metwalli
Journal:  J Endourol       Date:  2017-07-20       Impact factor: 2.942

2.  What is the Optimal Management Strategy for Multifocal and Hereditary Kidney Cancer?

Authors:  Joseph A Baiocco; Adam R Metwalli
Journal:  J Ren Med       Date:  2017-04-01

Review 3.  Current strategies to diagnose and manage positive surgical margins and local recurrence after partial nephrectomy.

Authors:  Umberto Carbonara; Daniele Amparore; Cosimo Gentile; Riccardo Bertolo; Selcuk Erdem; Alexandre Ingels; Michele Marchioni; Constantijn H J Muselaers; Onder Kara; Laura Marandino; Nicola Pavan; Eduard Roussel; Angela Pecoraro; Fabio Crocerossa; Giuseppe Torre; Riccardo Campi; Pasquale Ditonno
Journal:  Asian J Urol       Date:  2022-06-14

Review 4.  Multiplex Partial Nephrectomy, Repeat Partial Nephrectomy, and Salvage Partial Nephrectomy Remain the Primary Treatment in Multifocal and Hereditary Kidney Cancer.

Authors:  Joseph A Baiocco; Adam R Metwalli
Journal:  Front Oncol       Date:  2017-10-20       Impact factor: 6.244

  4 in total

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