Literature DB >> 27650429

CXCL4 in undifferentiated connective tissue disease at risk for systemic sclerosis (SSc) (previously referred to as very early SSc).

Gabriele Valentini1,2,3, Antonella Riccardi4,5,6, Serena Vettori4,5,6, Rosaria Irace4,5,6, Michele Iudici4,5,6, Salvatore Tolone4,5,6, Ludovico Docimo4,5,6, Marialuisa Bocchino4,5,6, Alessandro Sanduzzi4,5,6, Domenico Cozzolino4,5,6.   

Abstract

The aim of the study was to evaluate CXCL4 levels in undifferentiated connective tissue disease at risk for SSc (UCTD-SSc-risk) and confirm its increase and investigate its prognostic value. Serum CXCL4 levels were measured in 45 patients and 24 controls. CXCL4 was significantly higher in UCTD-SSc-risk patients than in controls. It resulted higher in patients with a shorter disease duration and in those lacking capillaroscopic alterations. We confirm that CXCL4 levels are increased in UCTD-risk-SSc patients. Further studies are needed to investigate the role of CXCL4 assessment in UCTD-risk-SSc.

Entities:  

Keywords:  Systemic sclerosis; Undifferentiated connective tissue disease

Mesh：

Substances：

Year:  2016        PMID： 27650429     DOI： 10.1007/s10238-016-0437-y

Source DB:  PubMed          Journal:  Clin Exp Med        ISSN： 1591-8890            Impact factor:   3.984


  14 in total

1.  2013 classification criteria for systemic sclerosis: an American College of Rheumatology/European League against Rheumatism collaborative initiative.

Authors:  Frank van den Hoogen; Dinesh Khanna; Jaap Fransen; Sindhu R Johnson; Murray Baron; Alan Tyndall; Marco Matucci-Cerinic; Raymond P Naden; Thomas A Medsger; Patricia E Carreira; Gabriela Riemekasten; Philip J Clements; Christopher P Denton; Oliver Distler; Yannick Allanore; Daniel E Furst; Armando Gabrielli; Maureen D Mayes; Jacob M van Laar; James R Seibold; Laszlo Czirjak; Virginia D Steen; Murat Inanc; Otylia Kowal-Bielecka; Ulf Müller-Ladner; Gabriele Valentini; Douglas J Veale; Madelon C Vonk; Ulrich A Walker; Lorinda Chung; David H Collier; Mary Ellen Csuka; Barri J Fessler; Serena Guiducci; Ariane Herrick; Vivien M Hsu; Sergio Jimenez; Bashar Kahaleh; Peter A Merkel; Stanislav Sierakowski; Richard M Silver; Robert W Simms; John Varga; Janet E Pope
Journal:  Arthritis Rheum       Date:  2013-10-03

2.  Very early versus early disease: the evolving definition of the 'many faces' of systemic sclerosis.

Authors:  Marco Matucci-Cerinic; Silvia Bellando-Randone; Gemma Lepri; Cosimo Bruni; Serena Guiducci
Journal:  Ann Rheum Dis       Date:  2012-11-23       Impact factor: 19.103

Review 3.  Angiogenesis and vasculogenesis in systemic sclerosis.

Authors:  J H W Distler; S Gay; O Distler
Journal:  Rheumatology (Oxford)       Date:  2006-10       Impact factor: 7.580

4.  Microvascular abnormalities in patients with early systemic sclerosis: less severe morphological changes than in patients with definite disease.

Authors:  C Z Camargo; J Y Sekiyama; M I Arismendi; C Kayser
Journal:  Scand J Rheumatol       Date:  2014-11-07       Impact factor: 3.641

5.  Preliminary criteria for the very early diagnosis of systemic sclerosis: results of a Delphi Consensus Study from EULAR Scleroderma Trials and Research Group.

Authors:  J Avouac; J Fransen; U A Walker; V Riccieri; V Smith; C Muller; I Miniati; I H Tarner; S Bellando Randone; M Cutolo; Y Allanore; O Distler; G Valentini; L Czirjak; U Müller-Ladner; D E Furst; A Tyndall; M Matucci-Cerinic
Journal:  Ann Rheum Dis       Date:  2010-11-15       Impact factor: 19.103

6.  Systemic sclerosis sine scleroderma: demographic, clinical, and serologic features and survival in forty-eight patients.

Authors:  H Poormoghim; M Lucas; N Fertig; T A Medsger
Journal:  Arthritis Rheum       Date:  2000-02

Review 7.  Undifferentiated Connective Tissue Disease at risk for systemic sclerosis (SSc) (so far referred to as very early/early SSc or pre-SSc).

Authors:  Gabriele Valentini
Journal:  Autoimmun Rev       Date:  2014-11-18       Impact factor: 9.754

8.  Increased serum type I interferon activity in early systemic sclerosis patients is associated with antibodies against Sjögren's syndrome antigens and nuclear ribonucleoprotein antigens.

Authors:  D M Wuttge; C Lood; E Tufvesson; A Scheja; L Truedsson; A A Bengtsson; R Hesselstrand
Journal:  Scand J Rheumatol       Date:  2013-02-05       Impact factor: 3.641

9.  Early systemic sclerosis: analysis of the disease course in patients with marker autoantibody and/or capillaroscopic positivity.

Authors:  Gabriele Valentini; Antonella Marcoccia; Giovanna Cuomo; Serena Vettori; Michele Iudici; Francesco Bondanini; Carlo Santoriello; Aldo Ciani; Domenico Cozzolino; Giovanni Maria De Matteis; Salvatore Cappabianca; Filiberto Vitelli; Alberto Spanò
Journal:  Arthritis Care Res (Hoboken)       Date:  2014-10       Impact factor: 4.794

10.  Early systemic sclerosis: marker autoantibodies and videocapillaroscopy patterns are each associated with distinct clinical, functional and cellular activation markers.

Authors:  Gabriele Valentini; Antonella Marcoccia; Giovanna Cuomo; Serena Vettori; Michele Iudici; Francesco Bondanini; Carlo Santoriello; Aldo Ciani; Domenico Cozzolino; Giovanni Maria De Matteis; Salvatore Cappabianca; Filiberto Vitelli; Alberto Spanò
Journal:  Arthritis Res Ther       Date:  2013       Impact factor: 5.156
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  1 in total

Review 1.  Precursors to Systemic Sclerosis and Systemic Lupus Erythematosus: From Undifferentiated Connective Tissue Disease to the Development of Identifiable Connective Tissue Diseases.

Authors:  Leonardo Martin Calderon; Janet E Pope
Journal:  Front Immunol       Date:  2022-05-05       Impact factor: 8.786
  1 in total

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