Literature DB >> 2764908

Mass spectrometric detection of cross-linked fatty acids formed during radical-induced lesion of lipid membranes.

H Frank1, D Thiel, J MacLeod.   

Abstract

A mass spectrometric method is described for the quantitative determination of dimers of polyunsaturated fatty acids (PUFA) formed in the hepatic endoplasmic reticulum of rats upon inhalation of tetrachloromethane. The results show that dimers account for a considerable fraction of microsomal PUFA which disappear during CCl4 metabolism. Cross-linking of the membrane lipids of the endoplasmic reticulum seems to be a significant process with respect to cell toxicity.

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Year:  1989        PMID： 2764908      PMCID： PMC1138757          DOI： 10.1042/bj2600873

Source DB:  PubMed          Journal:  Biochem J        ISSN： 0264-6021            Impact factor:   3.857


  24 in total

1.  The thiobarbituric acid reagent as a test for the oxidation of unsaturated fatty acids by various agents.

Authors:  K M WILBUR; F BERNHEIM; O W SHAPIRO
Journal:  Arch Biochem       Date:  1949-12

2.  Radon-222 from the island of hawaii: deep soils are more important than lava fields or volcanoes.

Authors:  M H Wilkening
Journal:  Science       Date:  1974-02-01       Impact factor: 47.728

3.  Mechanism of rat liver microsomal stearyl-CoA desaturase. Studies of the substrate specificity, enzyme-substrate interactions, and the function of lipid.

Authors:  H G Enoch; A Catalá; P Strittmatter
Journal:  J Biol Chem       Date:  1976-08-25       Impact factor: 5.157

4.  Characteristic lesions of methylazoxymethanol-induced liver damage. A comparative ultrastructural study with dimethylnitrosamine, hydrazine sulfate, and carbon tetrachloride.

Authors:  C E Ganote; A S Rosenthal
Journal:  Lab Invest       Date:  1968-10       Impact factor: 5.662

5.  Hepatic delta 9 and delta 6 desaturase activities during the recovery period following carbon tetrachloride poisoning.

Authors:  J Carreau; D Frommel; T T Nguyen; P Mazliak
Journal:  Lipids       Date:  1980-09       Impact factor: 1.880

6.  Calcium uptake of a rat liver microsomal subcellular fraction in response to in vivo administration of carbon tetrachloride.

Authors:  L Moore; G Rodman Davenport; E J Landon
Journal:  J Biol Chem       Date:  1976-02-25       Impact factor: 5.157

7.  The origin and structures of dimeric fatty acids from the anaerobic reaction between soya-bean lipoxygenase, linoleic acid and its hydroperoxide.

Authors:  G J Garssen; J F Vliegenthart; J Boldingh
Journal:  Biochem J       Date:  1972-11       Impact factor: 3.857

8.  Separation and characterization of the aldehydic products of lipid peroxidation stimulated by ADP-Fe2+ in rat liver microsomes.

Authors:  H Esterbauer; K H Cheeseman; M U Dianzani; G Poli; T F Slater
Journal:  Biochem J       Date:  1982-10-15       Impact factor: 3.857

9.  The role of CCl4 biotransformation in the activation of hepatocyte phospholipase C in vivo and in vitro.

Authors:  J B Coleman; L W Condie; R G Lamb
Journal:  Toxicol Appl Pharmacol       Date:  1988-09-15       Impact factor: 4.219

10.  High-performance liquid chromatography and gas chromatography-mass spectrometry determination of specific lipid peroxidation products in vivo.

Authors:  H Hughes; C V Smith; E C Horning; J R Mitchell
Journal:  Anal Biochem       Date:  1983-04-15       Impact factor: 3.365
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  7 in total

1.  Hydroxyproline reaction with free radicals generated during benzoyl peroxide catalytic decomposition of carbon tetrachloride Structure of reaction products formed.

Authors:  G D Castro; J A Castro
Journal:  Amino Acids       Date:  1996-09       Impact factor: 3.520

2.  Antioxidant effect of caffeic Acid on oxytetracycline induced lipid peroxidation in albino rats.

Authors:  R Jayanthi; P Subash
Journal:  Indian J Clin Biochem       Date:  2010-10-05

3.  Thymosin beta 4 prevents oxidative stress by targeting antioxidant and anti-apoptotic genes in cardiac fibroblasts.

Authors:  Sandeep Kumar; Sudhiranjan Gupta
Journal:  PLoS One       Date:  2011-10-25       Impact factor: 3.240

4.  The protective effect of caffeic acid on global cerebral ischemia-reperfusion injury in rats.

Authors:  Guojuan Liang; Bin Shi; Weinan Luo; Junqing Yang
Journal:  Behav Brain Funct       Date:  2015-04-18       Impact factor: 3.759

5.  Antioxidant and Cytotoxic Activities and Phytochemical Analysis of Euphorbia wallichii Root Extract and its Fractions.

Authors:  Ihsan Ul-Haq; Nazif Ullah; Gulnaz Bibi; Simab Kanwal; Muhammad Sheeraz Ahmad; Bushra Mirza
Journal:  Iran J Pharm Res       Date:  2012       Impact factor: 1.696

6.  Artifactual FA dimers mimic FAHFA signals in untargeted metabolomics pipelines.

Authors:  Alisa B Nelson; Lisa S Chow; Curtis C Hughey; Peter A Crawford; Patrycja Puchalska
Journal:  J Lipid Res       Date:  2022-03-18       Impact factor: 6.676

Review 7.  Mechanisms of Photosensitized Lipid Oxidation and Membrane Permeabilization.

Authors:  Isabel O L Bacellar; Mauricio S Baptista
Journal:  ACS Omega       Date:  2019-12-12
  7 in total

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