Ríona Ní Ghriallais1, Kevin Heraty2, Bob Smouse3, Martin Burke2, Paul Gilson2, Mark Bruzzi4. 1. Department of Biomedical Engineering, National University of Ireland, Galway, Ireland rionanighriallais@gmail.com. 2. Veryan Medical, Galway Technology Park, Parkmore, Galway, Ireland. 3. Department of Radiology, University of Illinois College of Medicine, Peoria, IL, USA. 4. Department of Biomedical Engineering, National University of Ireland, Galway, Ireland.
Abstract
PURPOSE: To quantify the deformation behavior of the diseased femoropopliteal segment and assess the change to deformation behavior due to various stent placements. METHODS: The length and curvature changes of 6 femoropopliteal segments (the right and left superficial femoral and popliteal arteries) from 3 cadavers were measured in 3-dimensional space based on rotational angiography image data in straight leg and flexed hip/knee (50°/90°) positions before and after placement of nitinol stents of varying type (EverFlex, Misago, and BioMimics 3D) and length (60, 100, and 200 mm) in different locations along the arteries. Three-dimensional centerline data were extracted for the measurements. RESULTS: All 6 femoropopliteal cadaver segments displayed signs of peripheral artery disease. Hip/knee flexion resulted in vessel shortening and increases in the mean and maximum vessel curvatures in all cases. Location-specific results of the unstented arteries showed that magnitudes of vessel length and curvature change vary as a function of vessel length. The average shortening of the entire femoropopliteal segment due to flexion was observed at 10.7%±0.7%, which was reduced to 8.1%±0.9% after stent deployment. Average and maximum curvatures of the unstented segment increased due to flexion (average: 0.008±0.002 mm-1 to 0.019±0.006 mm-1, maximum: 0.030±0.009 mm-1 to 0.091±0.045 mm-1). After stent deployment, average and maximum curvatures of the flexed stented segments increased compared with the flexed unstented segments (average: 0.019±0.006 mm-1 to 0.022±0.004 mm-1, maximum: 0.091±0.045 mm-1 to 0.103±0.025 mm-1). The most flexurally stiff stent demonstrated the least ability to axially shorten during flexion of the leg at the knee joint. CONCLUSION: The deformation characteristics of the femoropopliteal segment change in the presence of a stent, with the change to the deformation behavior dependent on stent type, stent length, location, flexibility, and intrinsic centerline curvature.
PURPOSE: To quantify the deformation behavior of the diseased femoropopliteal segment and assess the change to deformation behavior due to various stent placements. METHODS: The length and curvature changes of 6 femoropopliteal segments (the right and left superficial femoral and popliteal arteries) from 3 cadavers were measured in 3-dimensional space based on rotational angiography image data in straight leg and flexed hip/knee (50°/90°) positions before and after placement of nitinol stents of varying type (EverFlex, Misago, and BioMimics 3D) and length (60, 100, and 200 mm) in different locations along the arteries. Three-dimensional centerline data were extracted for the measurements. RESULTS: All 6 femoropopliteal cadaver segments displayed signs of peripheral artery disease. Hip/knee flexion resulted in vessel shortening and increases in the mean and maximum vessel curvatures in all cases. Location-specific results of the unstented arteries showed that magnitudes of vessel length and curvature change vary as a function of vessel length. The average shortening of the entire femoropopliteal segment due to flexion was observed at 10.7%±0.7%, which was reduced to 8.1%±0.9% after stent deployment. Average and maximum curvatures of the unstented segment increased due to flexion (average: 0.008±0.002 mm-1 to 0.019±0.006 mm-1, maximum: 0.030±0.009 mm-1 to 0.091±0.045 mm-1). After stent deployment, average and maximum curvatures of the flexed stented segments increased compared with the flexed unstented segments (average: 0.019±0.006 mm-1 to 0.022±0.004 mm-1, maximum: 0.091±0.045 mm-1 to 0.103±0.025 mm-1). The most flexurally stiff stent demonstrated the least ability to axially shorten during flexion of the leg at the knee joint. CONCLUSION: The deformation characteristics of the femoropopliteal segment change in the presence of a stent, with the change to the deformation behavior dependent on stent type, stent length, location, flexibility, and intrinsic centerline curvature.
Authors: Kaspars Maleckis; Eric Anttila; Paul Aylward; William Poulson; Anastasia Desyatova; Jason MacTaggart; Alexey Kamenskiy Journal: Ann Biomed Eng Date: 2018-02-22 Impact factor: 3.934
Authors: Jason MacTaggart; William Poulson; Andreas Seas; Paul Deegan; Carol Lomneth; Anastasia Desyatova; Kaspars Maleckis; Alexey Kamenskiy Journal: Ann Surg Date: 2019-07 Impact factor: 13.787