| Literature DB >> 27645785 |
Mateus Santana do Rosário1, Pedro Antonio Pereira de Jesus1, Nikos Vasilakis2,3, Daniel Santana Farias1, Marco Antônio Caires Novaes4, Sueli Guerreiro Rodrigues5, Lívia Caricio Martins5, Pedro Fernando da Costa Vasconcelos5, Albert Icksang Ko6, Luiz Carlos Junior Alcântara7, Isadora Cristina de Siqueira8.
Abstract
Zika virus (ZIKV) is an emerging flavivirus, which has caused a widespread outbreak in the Americas. Shortly after its introduction in 2015, a cluster of cases with Guillain-Barré syndrome was detected in Brazil. Herein, we describe two cases from the city of Salvador, who developed ascending paresis after an acute exanthematous illness. The patients were admitted to the intensive care unit with tetraparesis and cranial nerve palsy, which resolved after intravenous administration of human immunoglobulin. Serological evaluation detected IgM-specific ZIKV antibodies. In regions of Zika virus transmission, health-care workers must be aware of the potential severe neurological complications associated with ZIKV infection and be prepared to provide prompt diagnosis, treatment, and supportive care. © The American Society of Tropical Medicine and Hygiene.Entities:
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Year: 2016 PMID： 27645785 PMCID： PMC5094232 DOI： 10.4269/ajtmh.16-0306
Source DB: PubMed Journal: Am J Trop Med Hyg ISSN： 0002-9637 Impact factor: 2.345