Literature DB >> 2764468

Radioiodination for therapy.

T Adam1.   

Abstract

A method for the radioiodination of antibodies for therapy is described. The method resulted in a high efficiency of labelling (88-94%) with negligible damage to the antibody. Good localisation of labelled antibody was demonstrated. Doses of radiation to operators were very low.

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Year:  1989        PMID： 2764468     DOI： 10.1177/000456328902600306

Source DB:  PubMed          Journal:  Ann Clin Biochem        ISSN： 0004-5632            Impact factor:   2.057


  5 in total

1.  Guidelines for information about therapy experiments: a proposal on best practice for recording experimental data on cancer therapy.

Authors:  Alejandra N González-Beltrán; May Y Yong; Gairin Dancey; Richard Begent
Journal:  BMC Res Notes       Date:  2012-01-06

2.  Radioimmunotherapy of colorectal carcinoma xenografts in nude mice with yttrium-90 A33 IgG and Tri-Fab (TFM).

Authors:  P Antoniw; A P Farnsworth; A Turner; A M Haines; A Mountain; J Mackintosh; D Shochat; J Humm; S Welt; L J Old; G T Yarranton; D J King
Journal:  Br J Cancer       Date:  1996-08       Impact factor: 7.640

3.  Radioimmunotherapy of metastatic colorectal tumours with iodine-131-labelled antibody to carcinoembryonic antigen: phase I/II study with comparative biodistribution of intact and F(ab')2 antibodies.

Authors:  D M Lane; K F Eagle; R H Begent; L D Hope-Stone; A J Green; J L Casey; P A Keep; A M Kelly; J A Ledermann; M G Glaser
Journal:  Br J Cancer       Date:  1994-09       Impact factor: 7.640

4.  A phase I trial of antibody directed enzyme prodrug therapy (ADEPT) in patients with advanced colorectal carcinoma or other CEA producing tumours.

Authors:  R J Francis; S K Sharma; C Springer; A J Green; L D Hope-Stone; L Sena; J Martin; K L Adamson; A Robbins; L Gumbrell; D O'Malley; E Tsiompanou; H Shahbakhti; S Webley; D Hochhauser; A J Hilson; D Blakey; R H J Begent
Journal:  Br J Cancer       Date:  2002-09-09       Impact factor: 7.640

5.  Use of 18F FDG PET and the short temporal response of Hodgkin's disease to RIT.

Authors:  Ewa Nowosinska; Pei San Chan; John R Buscombe
Journal:  World J Nucl Med       Date:  2018 Jul-Sep
  5 in total

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