Jorge Daniel Oldan1, Parth S Patel2. 1. Clinical Assistant Professor, Division of Nuclear Medicine, Department of Radiology. 2. Radiology Resident, Department of Radiology, University of North Carolina-Chapel Hill, Chapel Hill, NC.
Abstract
IMPORTANCE: Positron emission tomography/Computed tomography(PET/CT) is widely used for gynecologic cancers. OBJECTIVE: To determine when PET/CT should be used for gynecologic cancers. EVIDENCE ACQUISITION: PubMed was reviewed for articles on PET/CT of all gynecologic cancers. National Comprehensive Cancer Network, Society of Gynecologic Oncology, and American College of Radiology guidelines were reviewed. RESULTS: Whole-body PET/CT is useful for (1) initial staging of cervical and endometrial cancer, posttherapy assessment, radiation therapy planning, and posttreatment surveillance of cervical cancer, and (2) assessment of recurrence of cervical, endometrial, or ovarian cancer in the presence of symptoms. It is also useful for staging and recurrence of uterine sarcomas, and for staging of vulvar and vaginal cancer. CONCLUSIONS: Positron emission tomography/Computed tomography is clinically valuable for a variety of gynecologic cancers. RELEVANCE: PET/CT plays an important role in detection of initial disease and recurrence of gynecologic malignancies.
IMPORTANCE: Positron emission tomography/Computed tomography(PET/CT) is widely used for gynecologic cancers. OBJECTIVE: To determine when PET/CT should be used for gynecologic cancers. EVIDENCE ACQUISITION: PubMed was reviewed for articles on PET/CT of all gynecologic cancers. National Comprehensive Cancer Network, Society of Gynecologic Oncology, and American College of Radiology guidelines were reviewed. RESULTS: Whole-body PET/CT is useful for (1) initial staging of cervical and endometrial cancer, posttherapy assessment, radiation therapy planning, and posttreatment surveillance of cervical cancer, and (2) assessment of recurrence of cervical, endometrial, or ovarian cancer in the presence of symptoms. It is also useful for staging and recurrence of uterine sarcomas, and for staging of vulvar and vaginal cancer. CONCLUSIONS: Positron emission tomography/Computed tomography is clinically valuable for a variety of gynecologic cancers. RELEVANCE: PET/CT plays an important role in detection of initial disease and recurrence of gynecologic malignancies.