Literature DB >> 27640172

Production and purification of Scandium-47: A potential radioisotope for cancer theranostics.

Leila Deilami-Nezhad1, Leila Moghaddam-Banaem2, Mahdi Sadeghi3, Mehdi Asgari2.   

Abstract

In this study, production of 47Sc radionuclide by irradiating the natural titanium dioxide powder (TiO2) in the fast neutron flux (~3*1013ncm-2s-1) for 4 days in Tehran Research Reactor (TRR, Iran) and separation from titanium target was investigated. The study showed the feasibility of production 47Sc by TRR. The separation efficiency and radiochemical purity (ScCl3) of radio-scandium, 47Sc radionuclide purity were obtained 98%, 99% and 88% respectively.
Copyright © 2016 Elsevier Ltd. All rights reserved.

Entities:  

Keywords:  Cation exchange chromatography; Natural titanium; Reactor production; Scandium-47

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Year:  2016        PMID： 27640172     DOI： 10.1016/j.apradiso.2016.09.004

Source DB:  PubMed          Journal:  Appl Radiat Isot        ISSN： 0969-8043            Impact factor:   1.513


  2 in total

Review 1.  Production of scandium radionuclides for theranostic applications: towards standardization of quality requirements.

Authors:  R Mikolajczak; S Huclier-Markai; C Alliot; F Haddad; D Szikra; V Forgacs; P Garnuszek
Journal:  EJNMMI Radiopharm Chem       Date:  2021-05-25

2.  The Preparation, Biodistribution, and Dosimetry of Encapsulated Radio-Scandium in a Dendrimer for Radio-nano-pharmaceutical Application.

Authors:  Leila Moghaddam-Banaem; Navideh Aghaei Amirkhizi; Sodeh Sadjadi; Fariba Johari-Deha; Mitra Athari-Allaf
Journal:  Iran J Pharm Res       Date:  2022-05-08       Impact factor: 1.962
  2 in total

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