| Literature DB >> 27639658 |
David M Shackleford1, Kris M Jamsen2.
Abstract
Estimating uncertainty in the ratio of 2 measured variables can be achieved via 2 seemingly different approaches: by determining the variance of the first-order Taylor approximation to the ratio, or by the so-called "Propagation of Error" approach. This Lesson Learned shows that the 2 approaches are mathematically equivalent, and provides an example of the approach.Keywords: ADME; bioavailability; caco-2 cells; in vitro models; pharmacokinetics
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Year: 2016 PMID: 27639658 DOI: 10.1016/j.xphs.2016.07.019
Source DB: PubMed Journal: J Pharm Sci ISSN: 0022-3549 Impact factor: 3.534