Literature DB >> 27638552

[Extracorporal shock wave therapy for the treatment of pseudarthrosis : New experiences with an old technology].

J Everding1, M Freistühler2, J Stolberg-Stolberg3, M J Raschke3, P Garcia3.   

Abstract

BACKGROUND: Between 5 and 10 % of all fractures show disturbed healing or nonunion formation. Extracorporeal shock wave therapy (ESWT) has been described as a non-surgical treatment option. Even though the outcome has shown promising results, the procedure is not commonly used in clinical practice. The purpose of this study was to analyze the union rate of pseudarthrosis and the cost savings after ESWT.
METHODS: In this study 42 nonunions were treated with shock waves (LithSpaceOrtho, JenaMedtech). The follow up examinations were performed over a period of six months. Outcome measurement included radiological fracture union and pain (VAS). The study group contained 39 pseudarthrosis in the six-week follow-up (93 %), 41 after three months (98 %) and 41 after six months (98 %).
RESULTS: After six weeks, 13 % of patients showed fracture union. After three months 61 % and after six months 73 % of the fractures were completely healed. The fracture healing was significantly lower in older nonunions. All patients presented significantly lower pain levels six weeks after ESWT. Shock wave treatment of all 42 pseudarthrosis made up less than one quarter of the overall operative costs.
CONCLUSION: We established the ESWT as an important treatment option for fracture nonunion in our clinic. Considering the selection of patients in this study with a high mean time from injury to ESWT and multiple prior operations, the fracture healing rate of 73 % after ESWT is comparable with operative healing rates of nonunions. Further prospective, randomized and controlled studies are needed to show the effectiveness of ESWT in the treatment of nonunions on a higher level of evidence and to identify pseudarthrosis that particularly responds to the EWST.

Entities:  

Keywords:  Cost savings; Extracorporeal shock wave therapy; Fracture healing; Pseudarthrosis; Shock wave therapy

Mesh:

Year:  2017        PMID: 27638552     DOI: 10.1007/s00113-016-0238-5

Source DB:  PubMed          Journal:  Unfallchirurg        ISSN: 0177-5537            Impact factor:   1.000


  42 in total

1.  [Extracorporeal shock wave therapy for delayed union of long bone fractures - preliminary results of a prospective cohort study].

Authors:  S Beutler; G Regel; H C Pape; S Machtens; A M Weinberg; I Kremeike; U Jonas; H Tscherne
Journal:  Unfallchirurg       Date:  1999-11       Impact factor: 1.000

2.  Smoking increases failure rate of operation for established non-union of the scaphoid bone.

Authors:  A F Dinah; R H Vickers
Journal:  Int Orthop       Date:  2006-09-01       Impact factor: 3.075

3.  Development of a prognostic naive bayesian classifier for successful treatment of nonunions.

Authors:  Alexander Stojadinovic; Benjamin Kyle Potter; John Eberhardt; Scott B Shawen; Romney C Andersen; Jonathan A Forsberg; Clay Shwery; Eric A Ester; Wolfgang Schaden
Journal:  J Bone Joint Surg Am       Date:  2011-01-19       Impact factor: 5.284

4.  Extracorporeal shock wave therapy for nonunion of the tibia.

Authors:  Eric A Elster; Alexander Stojadinovic; Jonathan Forsberg; Scott Shawen; Romney C Andersen; Wolfgang Schaden
Journal:  J Orthop Trauma       Date:  2010-03       Impact factor: 2.512

5.  Physical shock wave mediates membrane hyperpolarization and Ras activation for osteogenesis in human bone marrow stromal cells.

Authors:  F S Wang; C J Wang; H J Huang; H Chung; R F Chen; K D Yang
Journal:  Biochem Biophys Res Commun       Date:  2001-09-28       Impact factor: 3.575

6.  Morbidity at bone graft donor sites.

Authors:  E M Younger; M W Chapman
Journal:  J Orthop Trauma       Date:  1989       Impact factor: 2.512

7.  Extracorporeal shockwaves versus surgery in the treatment of pseudoarthrosis of the carpal scaphoid.

Authors:  A Notarnicola; L Moretti; S Tafuri; S Gigliotti; S Russo; L Musci; B Moretti
Journal:  Ultrasound Med Biol       Date:  2010-08       Impact factor: 2.998

8.  Application of shock waves to rat skin decreases calcitonin gene-related peptide immunoreactivity in dorsal root ganglion neurons.

Authors:  Norimasa Takahashi; Yuichi Wada; Seiji Ohtori; Takashi Saisu; Hideshige Moriya
Journal:  Auton Neurosci       Date:  2003-09-30       Impact factor: 3.145

9.  Nonunion of the tibia treated with a reamed intramedullary nail.

Authors:  D A Wiss; W B Stetson
Journal:  J Orthop Trauma       Date:  1994       Impact factor: 2.512

10.  Effects of extracorporeal shock wave therapy on fracture nonunions.

Authors:  Maria C Vulpiani; Mario Vetrano; Federica Conforti; Lucia Minutolo; Donatella Trischitta; John P Furia; Andrea Ferretti
Journal:  Am J Orthop (Belle Mead NJ)       Date:  2012-09
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  6 in total

1.  [Physical treatment options with impact on bone healing].

Authors:  M Arand
Journal:  Unfallchirurg       Date:  2019-07       Impact factor: 1.000

2.  [Pseudarthroses of the long bones].

Authors:  J Everding; S Roßlenbroich; M J Raschke
Journal:  Chirurg       Date:  2018-01       Impact factor: 0.955

3.  Effect of unfocused extracorporeal shockwave therapy on bone mineral content of twelve distal forearms of postmenopausal women: a clinical pilot study.

Authors:  Marianne K E Koolen; Moyo C Kruyt; Fetullah C Öner; Wolfgang Schaden; Harrie Weinans; Olav P van der Jagt
Journal:  Arch Osteoporos       Date:  2019-11-26       Impact factor: 2.617

4.  Safe and Effective Treatment of Compromised Clavicle Fracture of the Medial and Lateral Third Using Focused Shockwaves.

Authors:  Rainer Mittermayr; Nicolas Haffner; Sebastian Eder; Jonas Flatscher; Wolfgang Schaden; Paul Slezak; Cyrill Slezak
Journal:  J Clin Med       Date:  2022-04-02       Impact factor: 4.241

5.  Addition of shock wave therapy to nail dynamization increases the chance of long-bone non-union healing.

Authors:  Josef Stolberg-Stolberg; Thomas Fuchs; Moritz F Lodde; Steffen Roßlenbroich; Patric Garcia; Michael Raschke; Jens Everding
Journal:  J Orthop Traumatol       Date:  2022-01-08

Review 6.  Strategies to Improve Bone Healing: Innovative Surgical Implants Meet Nano-/Micro-Topography of Bone Scaffolds.

Authors:  Dirk Wähnert; Johannes Greiner; Stefano Brianza; Christian Kaltschmidt; Thomas Vordemvenne; Barbara Kaltschmidt
Journal:  Biomedicines       Date:  2021-06-28
  6 in total

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