Michala Kehrer1,2, Jesper Hallas3, Jesper Bælum4, Thøger Gorm Jensen5, Court Pedersen2, Annmarie Touborg Lassen1,6. 1. a Department of Clinical Research , University of Southern Denmark , Odense , Denmark. 2. b Department of Infectious Diseases, Odense University Hospital , Odense , Denmark. 3. c Department of Clinical Biochemistry and Pharmacology , Odense University Hospital , Odense , Denmark. 4. d Occupational and Environmental Medicine , University of Southern Denmark , Odense , Denmark. 5. e Department of Clinical Microbiology , Odense University Hospital , Odense , Denmark. 6. f Department of Emergency Medicine , Odense University Hospital , Odense , Denmark.
Abstract
BACKGROUND: As little is known about the ability to work in patients with infectious spondylodiscitis, we compared the relation between the workforce before infection with that of a reference population and described the patients' ability to work after infection including predictors of return to work (RTW). METHODS: We identified all patients aged 20-57 years treated for infectious spondylodiscitis January 1994-May 2009 at hospitals in Funen County, Denmark. The work status of each week from 2 years before until 2 years after index date was compared with that of a reference population. Time to RTW was described using cumulative incidence curves and univariate cause-specific Cox-regression analyses (hazard ratios - HRs). RESULTS: Of 112 identified patients, 8 (7%) died within the first year and 48 (43%) were part of the workforce 1 year before index. Through the entire observation period, the patients had lower affiliation to the workforce compared with the reference population. During the observation period, the proportion of patients on permanent disability pension increased from 24% to 38% and the proportion of self-supporters decreased from 58% to 33%. Seventy-three per cent of the patients being part of the workforce 1 year before index returned to the workforce within the 2 year follow-up. Main predictor of RTW was being part of the workforce 1 year before index (HR = 7.8; CI: 2.4-25.3). CONCLUSIONS: Patients with infectious spondylodiscitis were less likely to be part of the workforce before infection compared with a reference population and infection further lowered their ability to RTW.
BACKGROUND: As little is known about the ability to work in patients with infectious spondylodiscitis, we compared the relation between the workforce before infection with that of a reference population and described the patients' ability to work after infection including predictors of return to work (RTW). METHODS: We identified all patients aged 20-57 years treated for infectious spondylodiscitis January 1994-May 2009 at hospitals in Funen County, Denmark. The work status of each week from 2 years before until 2 years after index date was compared with that of a reference population. Time to RTW was described using cumulative incidence curves and univariate cause-specific Cox-regression analyses (hazard ratios - HRs). RESULTS: Of 112 identified patients, 8 (7%) died within the first year and 48 (43%) were part of the workforce 1 year before index. Through the entire observation period, the patients had lower affiliation to the workforce compared with the reference population. During the observation period, the proportion of patients on permanent disability pension increased from 24% to 38% and the proportion of self-supporters decreased from 58% to 33%. Seventy-three per cent of the patients being part of the workforce 1 year before index returned to the workforce within the 2 year follow-up. Main predictor of RTW was being part of the workforce 1 year before index (HR = 7.8; CI: 2.4-25.3). CONCLUSIONS:Patients with infectious spondylodiscitis were less likely to be part of the workforce before infection compared with a reference population and infection further lowered their ability to RTW.
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Vertebral osteomyelitis; bone infection; prognosis; return to work; workforce
Authors: Tiziano A Schweizer; Federica Andreoni; Claudio Acevedo; Thomas C Scheier; Irina Heggli; Ewerton Marques Maggio; Nadia Eberhard; Silvio D Brugger; Stefan Dudli; Annelies S Zinkernagel Journal: Front Immunol Date: 2022-07-28 Impact factor: 8.786