Literature DB >> 27636703

Senescent cell death brings hopes to life.

Yossi Ovadya1, Valery Krizhanovsky1.   

Abstract

Keywords:  Aging; BCL-2; apoptosis; cell senescence; regeneration; senolytic; stem cells

Mesh：

Year:  2016        PMID： 27636703      PMCID： PMC5270519          DOI： 10.1080/15384101.2016.1232088

Source DB:  PubMed          Journal:  Cell Cycle        ISSN： 1551-4005            Impact factor:   4.534


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  7 in total

1.  Clearance of senescent cells by ABT263 rejuvenates aged hematopoietic stem cells in mice.

Authors:  Jianhui Chang; Yingying Wang; Lijian Shao; Remi-Martin Laberge; Marco Demaria; Judith Campisi; Krishnamurthy Janakiraman; Norman E Sharpless; Sheng Ding; Wei Feng; Yi Luo; Xiaoyan Wang; Nukhet Aykin-Burns; Kimberly Krager; Usha Ponnappan; Martin Hauer-Jensen; Aimin Meng; Daohong Zhou
Journal:  Nat Med       Date:  2015-12-14       Impact factor: 53.440

Review 2.  Cellular senescence in aging and age-related disease: from mechanisms to therapy.

Authors:  Bennett G Childs; Matej Durik; Darren J Baker; Jan M van Deursen
Journal:  Nat Med       Date:  2015-12       Impact factor: 53.440

3.  The Achilles' heel of senescent cells: from transcriptome to senolytic drugs.

Authors:  Yi Zhu; Tamara Tchkonia; Tamar Pirtskhalava; Adam C Gower; Husheng Ding; Nino Giorgadze; Allyson K Palmer; Yuji Ikeno; Gene B Hubbard; Marc Lenburg; Steven P O'Hara; Nicholas F LaRusso; Jordan D Miller; Carolyn M Roos; Grace C Verzosa; Nathan K LeBrasseur; Jonathan D Wren; Joshua N Farr; Sundeep Khosla; Michael B Stout; Sara J McGowan; Heike Fuhrmann-Stroissnigg; Aditi U Gurkar; Jing Zhao; Debora Colangelo; Akaitz Dorronsoro; Yuan Yuan Ling; Amira S Barghouthy; Diana C Navarro; Tokio Sano; Paul D Robbins; Laura J Niedernhofer; James L Kirkland
Journal:  Aging Cell       Date:  2015-04-22       Impact factor: 9.304

4.  Senescent cells communicate via intercellular protein transfer.

Authors:  Anat Biran; Meirav Perelmutter; Hilah Gal; Dominick G A Burton; Yossi Ovadya; Ezra Vadai; Tamar Geiger; Valery Krizhanovsky
Journal:  Genes Dev       Date:  2015-04-08       Impact factor: 11.361

5.  Stromal senescence establishes an immunosuppressive microenvironment that drives tumorigenesis.

Authors:  Megan K Ruhland; Andrew J Loza; Aude-Helene Capietto; Xianmin Luo; Brett L Knolhoff; Kevin C Flanagan; Brian A Belt; Elise Alspach; Kathleen Leahy; Jingqin Luo; Andras Schaffer; John R Edwards; Gregory Longmore; Roberta Faccio; David G DeNardo; Sheila A Stewart
Journal:  Nat Commun       Date:  2016-06-08       Impact factor: 14.919

6.  NKG2D ligands mediate immunosurveillance of senescent cells.

Authors:  Adi Sagiv; Dominick G A Burton; Zhana Moshayev; Ezra Vadai; Felix Wensveen; Shifra Ben-Dor; Ofra Golani; Bojan Polic; Valery Krizhanovsky
Journal:  Aging (Albany NY)       Date:  2016-02       Impact factor: 5.682

7.  Directed elimination of senescent cells by inhibition of BCL-W and BCL-XL.

Authors:  Reut Yosef; Noam Pilpel; Ronit Tokarsky-Amiel; Anat Biran; Yossi Ovadya; Snir Cohen; Ezra Vadai; Liat Dassa; Elisheva Shahar; Reba Condiotti; Ittai Ben-Porath; Valery Krizhanovsky
Journal:  Nat Commun       Date:  2016-04-06       Impact factor: 14.919
  7 in total
  4 in total

Review 1.  Targeting Cell Senescence for the Treatment of Age-Related Bone Loss.

Authors:  Robert J Pignolo; Rebekah M Samsonraj; Susan F Law; Haitao Wang; Abhishek Chandra
Journal:  Curr Osteoporos Rep       Date:  2019-04       Impact factor: 5.096

2.  Impaired immune surveillance accelerates accumulation of senescent cells and aging.

Authors:  Yossi Ovadya; Tomer Landsberger; Hanna Leins; Ezra Vadai; Hilah Gal; Anat Biran; Reut Yosef; Adi Sagiv; Amit Agrawal; Alon Shapira; Joseph Windheim; Michael Tsoory; Reinhold Schirmbeck; Ido Amit; Hartmut Geiger; Valery Krizhanovsky
Journal:  Nat Commun       Date:  2018-12-21       Impact factor: 14.919

Review 3.  Looking for immortality: Review of phytotherapy for stem cell senescence.

Authors:  Hourieh Tousian; Bibi Marjan Razavi; Hossein Hosseinzadeh
Journal:  Iran J Basic Med Sci       Date:  2020-02       Impact factor: 2.699

Review 4.  Implications of Oxidative Stress and Cellular Senescence in Age-Related Thymus Involution.

Authors:  Alexandra Barbouti; Panagiotis V S Vasileiou; Konstantinos Evangelou; Konstantinos G Vlasis; Alexandra Papoudou-Bai; Vassilis G Gorgoulis; Panagiotis Kanavaros
Journal:  Oxid Med Cell Longev       Date:  2020-02-05       Impact factor: 6.543
  4 in total

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