Literature DB >> 27634125

AL (Light-Chain) Cardiac Amyloidosis: A Review of Diagnosis and Therapy.

Rodney H Falk1, Kevin M Alexander2, Ronglih Liao2, Sharmila Dorbala3.   

Abstract

The amyloidoses are a group of protein-folding disorders in which ≥1 organ is infiltrated by proteinaceous deposits known as amyloid. The deposits are derived from 1 of several amyloidogenic precursor proteins, and the prognosis of the disease is determined both by the organ(s) involved and the type of amyloid. Amyloid involvement of the heart (cardiac amyloidosis) carries the worst prognosis of any involved organ, and light-chain (AL) amyloidosis is the most serious form of the disease. The last decade has seen considerable progress in understanding the amyloidoses. In this review, current and novel approaches to the diagnosis and treatment of cardiac amyloidosis are discussed, with particular reference to AL amyloidosis in the heart.
Copyright © 2016 American College of Cardiology Foundation. Published by Elsevier Inc. All rights reserved.

Entities:  

Keywords:  TTR amyloidosis; cardiomyopathy; multiple myeloma

Mesh：

Substances：

Year:  2016        PMID： 27634125     DOI： 10.1016/j.jacc.2016.06.053

Source DB:  PubMed          Journal:  J Am Coll Cardiol        ISSN： 0735-1097            Impact factor:   24.094


  119 in total

Review 1.  Utility of Cardiac Magnetic Resonance Imaging in the Diagnosis, Prognosis, and Treatment of Infiltrative Cardiomyopathies.

Authors:  Praveen G Ranganath; Albree Tower-Rader
Journal:  Curr Cardiol Rep       Date:  2021-06-03       Impact factor: 2.931

Review 2.  Advances in Treatment of Cardiac Amyloid.

Authors:  Cherie N Dahm; R Frank Cornell; Daniel J Lenihan
Journal:  Curr Treat Options Cardiovasc Med       Date:  2018-04-07

3.  The Role of Protein Thermodynamics and Primary Structure in Fibrillogenesis of Variable Domains from Immunoglobulin Light Chains.

Authors:  Enrico Rennella; Gareth J Morgan; Nicholas Yan; Jeffery W Kelly; Lewis E Kay
Journal:  J Am Chem Soc       Date:  2019-08-14       Impact factor: 15.419

Review 4.  Role of Imaging in Evaluating Infiltrative Heart Disease.

Authors:  Sanjay Divakaran; Avinainder Singh; Bradley Collins; Tomas Vita; Rodney H Falk; Marcelo F Di Carli; Ron Blankstein
Journal:  Curr Treat Options Cardiovasc Med       Date:  2017-01

5.  Assessment of prognosis in immunoglobulin light chain amyloidosis patients with severe heart failure: a predictive value of right ventricular function.

Authors:  Nobutaka Nagano; Toshiyuki Yano; Yugo Fujita; Hidemichi Kouzu; Masayuki Koyama; Hiroshi Ikeda; Kenji Yasui; Atsuko Muranaka; Ryo Nishikawa; Ryo Takahashi; Naohiro Kishiue; Satoshi Yuda; Tetsuji Miura
Journal:  Heart Vessels       Date:  2019-09-26       Impact factor: 2.037

6.  Simultaneous Tc-99m PYP/Tl-201 dual-isotope SPECT myocardial imaging in patients with suspected cardiac amyloidosis.

Authors:  Balaji Tamarappoo; Yuka Otaki; Osamu Manabe; Mark Hyun; Stephanie Cantu; Yoav Arnson; Heidi Gransar; Sean W Hayes; John D Friedman; Louise Thomson; Piotr Slomka; Damini Dey; Robert Vescio; Jignesh Patel; Daniel S Berman
Journal:  J Nucl Cardiol       Date:  2019-06-06       Impact factor: 5.952

Review 7.  Cardiac amyloidosis: An update on pathophysiology, diagnosis, and treatment.

Authors:  Omar K Siddiqi; Frederick L Ruberg
Journal:  Trends Cardiovasc Med       Date:  2017-07-13       Impact factor: 6.677

Review 8.  Transthyretin Amyloid Cardiomyopathy: JACC State-of-the-Art Review.

Authors:  Frederick L Ruberg; Martha Grogan; Mazen Hanna; Jeffery W Kelly; Mathew S Maurer
Journal:  J Am Coll Cardiol       Date:  2019-06-11       Impact factor: 24.094

9.  ASNC/AHA/ASE/EANM/HFSA/ISA/SCMR/SNMMI expert consensus recommendations for multimodality imaging in cardiac amyloidosis: Part 1 of 2-evidence base and standardized methods of imaging.

Authors:  Sharmila Dorbala; Yukio Ando; Sabahat Bokhari; Angela Dispenzieri; Rodney H Falk; Victor A Ferrari; Marianna Fontana; Olivier Gheysens; Julian D Gillmore; Andor W J M Glaudemans; Mazen A Hanna; Bouke P C Hazenberg; Arnt V Kristen; Raymond Y Kwong; Mathew S Maurer; Giampaolo Merlini; Edward J Miller; James C Moon; Venkatesh L Murthy; C Cristina Quarta; Claudio Rapezzi; Frederick L Ruberg; Sanjiv J Shah; Riemer H J A Slart; Hein J Verberne; Jamieson M Bourque
Journal:  J Nucl Cardiol       Date:  2019-12       Impact factor: 5.952

Review 10.  Microvascular dysfunction in infiltrative cardiomyopathies.

Authors:  Ornella Rimoldi; Francesco Maranta
Journal:  J Nucl Cardiol       Date:  2017-07-11       Impact factor: 5.952
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