Literature DB >> 27633592

Role of Histologic Inflammation in the Natural History of Ulcerative Colitis.

Deepa T Patil1, Alan C Moss2, Robert D Odze3.   

Abstract

The goals of therapy for ulcerative colitis have moved from symptom improvement to mucosal healing, and finally histologic resolution. The natural history of histologic inflammation in ulcerative colitis progresses from initial cellular infiltration to architectural disruption and recovery on medical therapy. Many studies have linked histologic changes to clinical outcomes, providing prognostic value to histologic abnormalities. This review covers all these components.
Copyright © 2016 Elsevier Inc. All rights reserved.

Entities:  

Keywords:  Histology; Prognosis; Severity; Ulcerative colitis

Mesh:

Year:  2016        PMID: 27633592     DOI: 10.1016/j.giec.2016.06.009

Source DB:  PubMed          Journal:  Gastrointest Endosc Clin N Am        ISSN: 1052-5157


  4 in total

1.  Costus root granules improve ulcerative colitis through regulation of TGF-β mediation of the PI3K/AKT signaling pathway.

Authors:  Xiaohong Wang; Dan Li; Yong Zhang; Shuang Wu; Fang Tang
Journal:  Exp Ther Med       Date:  2018-03-09       Impact factor: 2.447

2.  Complete histologic normalisation is associated with reduced risk of relapse among patients with ulcerative colitis in complete endoscopic remission.

Authors:  Kelly C Cushing; William Tan; David H Alpers; Vikram Deshpande; Ashwin N Ananthakrishnan
Journal:  Aliment Pharmacol Ther       Date:  2019-11-07       Impact factor: 8.171

3.  Infliximab trough concentrations during maintenance therapy are associated with endoscopic and histologic healing in ulcerative colitis.

Authors:  K Papamichael; S Rakowsky; C Rivera; A S Cheifetz; M T Osterman
Journal:  Aliment Pharmacol Ther       Date:  2017-12-06       Impact factor: 8.171

4.  Prognostic value of histological activity in patients with ulcerative colitis in deep remission: A prospective multicenter study.

Authors:  Triana Lobatón; Talat Bessissow; Alexandra Ruiz-Cerulla; Gert De Hertogh; Raf Bisschops; Jordi Guardiola; Gert Van Assche; Severine Vermeire; Marc Ferrante
Journal:  United European Gastroenterol J       Date:  2018-01-08       Impact factor: 4.623

  4 in total

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