Arshad Javaid1, Mazhar Ali Khan2, Mir Azam Khan3, Sumaira Mehreen4, Anila Basit1, Raza Ali Khan5, Muhammad Ihtesham4, Irfan Ullah4, Afsar Khan4, Ubaid Ullah4. 1. Post Graduate Medical Institute, Lady Reading Hospital, Peshawar, Pakistan; Programmatic Management of Drug Resistant TB Unit, Lady Reading Hospital, Peshawar, Pakistan. 2. Programmatic Management of Drug Resistant TB Unit, Lady Reading Hospital, Peshawar, Pakistan. Electronic address: mali_smile2005@yahoo.com. 3. Peshawar Medical College, Peshawar, Pakistan. 4. Programmatic Management of Drug Resistant TB Unit, Lady Reading Hospital, Peshawar, Pakistan. 5. Kohat University of Science and Technology, Kohat, Pakistan.
Abstract
OBJECTIVE: To assess the profile of TB/multidrug-resistant TB (MDR-TB) among household contacts of MDR-TB patients. METHODS: Close contacts of MDR-TB patients were traced in the cross-sectional study. Different clinical, radiological and bacteriological were performed to rule out the evidence of TB/MDR-TB. RESULTS: Between January 2012 and December 2012, a total of 200 index MDR-TB patients were initiated on MDR-TB treatment, out of which home visit and contacts screening were conducted for 154 index cases. Of 610 contacts who could be studied, 41 (17.4%) were diagnosed with MDR-TB and 10 (4.2%) had TB. The most common symptoms observed were cough, chest pain and fever. CONCLUSIONS: The high incidence of MDR-TB among close contacts emphasize the need for effective contact screening programme of index MDR-TB cases in order to cut the chain of transmission of this disease.
OBJECTIVE: To assess the profile of TB/multidrug-resistant TB (MDR-TB) among household contacts of MDR-TBpatients. METHODS: Close contacts of MDR-TBpatients were traced in the cross-sectional study. Different clinical, radiological and bacteriological were performed to rule out the evidence of TB/MDR-TB. RESULTS: Between January 2012 and December 2012, a total of 200 index MDR-TBpatients were initiated on MDR-TB treatment, out of which home visit and contacts screening were conducted for 154 index cases. Of 610 contacts who could be studied, 41 (17.4%) were diagnosed with MDR-TB and 10 (4.2%) had TB. The most common symptoms observed were cough, chest pain and fever. CONCLUSIONS: The high incidence of MDR-TB among close contacts emphasize the need for effective contact screening programme of index MDR-TB cases in order to cut the chain of transmission of this disease.
Authors: Yohhei Hamada; Philippe Glaziou; Charalambos Sismanidis; Haileyesus Getahun Journal: Bull World Health Organ Date: 2019-05-28 Impact factor: 9.408